The Metabolic Pathway Engineering Handbook: Fundamentals

ISBN 10: 1439802963 / ISBN 13: 9781439802960

Published by CRC Press, 2009

About this Item

In. Seller Inventory # ria9781439802960_new

Bibliographic Details

Title: The Metabolic Pathway Engineering Handbook: ...

Publisher: CRC Press

Publication Date: 2009

Binding: Hardcover

Condition: New

About this title

Synopsis:

This first volume of the Metabolic Pathway Engineering Handbook provides an overview of metabolic pathway engineering with a look towards the future. It discusses cellular metabolism, including transport processes inside the cell and energy generating reactions, as well as rare metabolic conversions. This volume also explores balances and reaction models, the regulation of metabolic pathways, and genome scale and multiscale modeling tools. It also covers developing appropriate hosts for metabolic engineering including the use of Escherichia coli, yeast, Bacillus Subtilis, Streptomyces, filamentous fungi, and mammalian cells using cell culture. Christine Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer’s yeast, is regarded as one of the most brilliant new minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metabolic pathway engineering. With a wealth of cutting edge research and analysis, this work also serves as an invaluable resource for those seeking to add their own contributions. Organized by topic, this 3000 page reference is available as two volumes that can be purchased individually or as a set. For information on the complete handbook visit Cat No. 3923

Synopsis:

This complete handbook on metabolic pathway engineering covers everything from fundamentals to advanced applications. Providing a thousand pages of material in two volumes, the first covers mass balances and reaction models as applied to predicting product formation and microbial growth in fermentation processes, transcriptional regulation of metabolic pathways in bacterial systems, and common cellular hosts used in metabolic engineering applications. Focusing then on metabolic engineering applications, the second volume covers evolutionary and gene expression tools, and emerging technologies. It also delves into common tools that are utilized to determine flux through metabolic pathways.