Membrane Transporter Diseases

Stefan Bröer

ISBN 10: 0306478838 / ISBN 13: 9780306478833

Published by Springer Us Mär 2004, 2004

About this Item

Neuware - Every cell and organism faces the problem of spaces, made up of the two leaflets of the lipid generating a confined space in which metabolic bilayer. The importance of traffic and signaling across membranes is reflected by the estimate and anabolic reactions take place and at the same time allowing entry and exit of metabo that 20% of all genes in the human genome encode membrane proteins. A failure of any of lites, ions, proteins, and signals across its bor der. Evolution has solved the problem by these proteins may have dramatic con se generating lipid membranes that contain trans quences for ceH function. In recent years much porters, ion channels, and receptors. In eukary attention has been paid to diseases resulting otic cells, this problem is exacerbated by the from nonfunctional ion channels ('chan presence of multiple organelles, which are con nelopathies'). Not surprisingly, many of these fined spaces in their own right. Even the lipid diseases affect the excitability of cells. membrane consists of two relatively separate Transporter diseases (perhaps coined 'carrier vi PREFACE diseases') are more related to metabolic dis Each chapter is concluded by a summary, and eases, Transporters are frequently found at the most chapters also contain an overview of the beginning or the end of metabolic pathways clinical features of a particular transporter and as a result can have similar effects to disease. a missing enzyme.

Seller Inventory # 9780306478833

Bibliographic Details

• Title: Membrane Transporter Diseases
• Publisher: Springer Us Mär 2004
• Publication Date: 2004
• Language: English
• ISBN 10: 0306478838
• ISBN 13: 9780306478833
• Binding: Buch
• Condition: Neu
• Dimensions: 254W x 178H x 30D millimeters 254 millimeters width by 178 millimeters height by 30 millimeters depth
• Weight: 1021 grams

About this title

Synopsis

Every cell and organism faces the problem of spaces, made up of the two leaflets of the lipid generating a confined space in which metabolic bilayer. The importance of traffic and signaling across membranes is reflected by the estimate and anabolic reactions take place and at the same time allowing entry and exit of metabo­ that 20% of all genes in the human genome encode membrane proteins. A failure of any of lites, ions, proteins, and signals across its bor­ der. Evolution has solved the problem by these proteins may have dramatic con se­ generating lipid membranes that contain trans­ quences for ceH function. In recent years much porters, ion channels, and receptors. In eukary­ attention has been paid to diseases resulting otic cells, this problem is exacerbated by the from nonfunctional ion channels ("chan­ presence of multiple organelles, which are con­ nelopathies"). Not surprisingly, many of these fined spaces in their own right. Even the lipid diseases affect the excitability of cells. membrane consists of two relatively separate Transporter diseases (perhaps coined "carrier vi PREFACE diseases") are more related to metabolic dis­ Each chapter is concluded by a summary, and eases, Transporters are frequently found at the most chapters also contain an overview of the beginning or the end of metabolic pathways clinical features of a particular transporter and as a result can have similar effects to disease. a missing enzyme.

Product Description

The unprecedented sensitivity of the Infrared Space Observatory and the far-infrared window provided by IRAS led to spectroscopic surveys throughout the entire infrared region. In particular, the high resolution allowed for pointed observations of individual sources. The authors of this volume are principal investigators of the ISO mission and present a host of new data analyses that should trigger novel astrophysical research in the far-infrared. A particular feature of the book is the emphasis on object-oriented presentation of the observations. The book addresses researchers and students alike.