Mathematical Modeling of Pharmacokinetic Data
Language: English
Published by CRC Press, Lancaster, Pa, 1995
- Hardcover
- Used
Seller: Fox & Tome Books, Frederick, MD, U.S.A.Fox & Tome Books
AbeBooks seller since March 2, 2023
Condition: Used - Fine
£ 46.14
Quantity: 1 available
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In excellent condition, no writing or markings, book is crisp and clean. 100% satisfaction guarantee. Shipped with care in a bubble mailer. Feel free to inquire for photos or more details. I hand inspect every item. --- A concise treatment of fitting mathematical models to pharmacokinetic data, by Steven Strauss and David W.A. Bourne. The opening chapters explain why data are modeled at all: to condense results, test mechanisms and make predictions. They then set out a general fitting method. The authors cover compartmental, physiologically based and pharmacodynamic models, and show how to simulate data from explicit and implicit equations and from differential equations, using Laplace transforms or numerical integration. Later chapters deal with getting initial parameter estimates through graphical methods, linear regression, curve stripping, area-under-the-curve estimation and deconvolution. They also cover non-linear regression algorithms, including grid search, steepest descent, Gauss-Newton and simplex, along with the problem of local minima. Weighting schemes range from equal weights to extended least squares and Bayesian methods, and population data are also treated. The book closes with chapters on reading program output and on experimental design. …
Seller Inventory # OA-240115-shelf-18-050
- Title
- Mathematical Modeling of Pharmacokinetic Data
- Author
- Steven Strauss; David W.A. Bourne
- Publisher
- CRC Press, Lancaster, Pa
- Publication year
- 1995
- Condition
- Fine
- Binding
- Hardback
- Language
- English
- ISBN 10
- 1566762049
- ISBN 13
- 9781566762045
- Item weight
- 2 pounds
- Dimensions
- 14.0 x 14.0 x 4.0 inches
- Seller catalogs
- Medicine, Medicine & Health
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Fox & Tome Books
Frederick, MD, U.S.A.
AbeBooks seller since March 2, 2023
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Fox & Tome Books is an independent online bookshop based in Frederick, Maryland, with 13 years in the trade. The store is not huge but runs wide categorically: history, military, art, photography, science and medicine, religious studies of all faiths, occult, scholarship and reference, signed copies, first editions, the scarce and out-of-print. Don’t forget the esoteric hodgepodge/occasional risqué title. Every book is hand inspected, accurately described and shipped with care. Please inquire about any item for details or additional photos. Thanks. -Brandon…
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Fox & Tome Books
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