MODEL ORGANISMS IN DRUG DISCOVERY
Language: English
Published by Wiley, 2003
- Hardcover
- New

Seller: Basi6 International, Irving, TX, U.S.A.Basi6 International
AbeBooks seller since June 24, 2016
Condition: New
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- Title
- MODEL ORGANISMS IN DRUG DISCOVERY
- Author
- Carroll
- Publisher
- Wiley
- Publication year
- 2003
- Condition
- Brand New
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 0470848936
- ISBN 13
- 9780470848937
Feed a fruit fly caffeine and it has trouble falling asleep; feed it antihistamines and it cannot stay awake. A C. elegans worm placed on the antidepressant flouxetine has increased serotonin levels in its tiny brain. Yeast treated with chemotherapeutics stop their cell division. Removal of a single gene from a mouse or zebrafish can cause the animals to develop Alzheimer’s disease or heart disease. These organisms are utilized as surrogates to investigate the function and design of complex human biological systems.
Advances in bioinformatics, proteomics, automation technologies and their application to model organism systems now occur on an industrial scale. The integration of model systems into the drug discovery process, the speed of the tools, and the in vivo validation data that these models can provide, will clearly help definition of disease biology and high-quality target validation. Enhanced target selection will lead to the more efficacious and less toxic therapeutic compounds of the future.
Leading experts in the field provide detailed accounts of model organism research that have impacted on specific therapeutic areas and they examine state-of-the-art applications of model systems, describing real life applications and their possible impact in the future.
This book will be of interest to geneticists, bioinformaticians, pharmacologists, molecular biologists and people working in the pharmaceutical industry, particularly genomics.
"Synopsis" may belong to another edition of this title.
About the Author
Pamela M. Carroll is the editor of Model Organisms in Drug Discovery, published by Wiley.
Kevin Fitzgerald is the editor of Model Organisms in Drug Discovery, published by Wiley.
"About the title" may belong to another edition of this title.
Basi6 International
Irving, TX, U.S.A.
AbeBooks seller since June 24, 2016
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