MATRIX METALLOPROTEINASES IN THE CENTRAL NERVOUS SYSTEM

ISBN 10: 1860945597 / ISBN 13: 9781860945595

Published by Imperial College Press, 2005

Gently read. May have name of previous ownership, or ex-library edition. Binding tight; spine straight and smooth, with no creasing; covers clean and crisp. Minimal signs of handling or shelving. 100% GUARANTEE! Shipped with delivery confirmation, if you're not satisfied with purchase please return item! Ships USPS Media Mail. Seller Inventory # OTV.1860945597.VG

Synopsis:

This book presents the reader with an understanding of the role played by matrix metalloproteinases (MMPs) in the normal and diseased central nervous system (CNS). These enzymes may be important to brain development, and may also contribute to tissue destruction, which is observed with inflammatory and degenerative conditions of the brain. The book provides a background on the biology of MMPs, and on the stimuli and conditions that are linked to an increase in their production and activity. It describes the targets of MMPs, which include matrix proteins such as collagen, soluble cytokines and chemokines, and cell surface receptors. Studies implicating MMPs in neuronal process outgrowth and cell migration in CNS development are covered. The book also touches on studies suggesting that, in certain situations, dysregulated MMP activity and/or production may be critical to blood-brain barrier breakdown and neuronal damage.

Bibliographic Details

Title: MATRIX METALLOPROTEINASES IN THE CENTRAL ...
Publisher: Imperial College Press
Publication Date: 2005
Binding: Hardcover
Condition: very_good