Low Dose Exposures in the Environment: Dose-Effect Relations and Risk Evaluation (Ethics of Science and Technology Assessment, 23)
Language: English
Published by Springer, 2004
- Hardcover
- Used
Seller: killarneybooks, Inagh, Clare, Irelandkillarneybooks
AbeBooks seller since April 20, 2017
Condition: Used - Good
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Add to basketItem description from seller
Hardcover, 470pp, NOT ex-library. Clean book, with unmarked text, no stamps. A small indentation to some lower outer page corners. Handling marks on boards; rubbed upper front board at spine. Issued without a dust jacket. -- Contents: Ethical Aspects of Risk [Rational Decision Making (Decision Makers; Alternatives; Probabilities of Consequences. Precautionary Principle; Utilitarianism & Consequentialism; Values; Time; Life; Health; Environmental Values; Known Individuals or Anonymous Ones; Free Choice; Consent; Distribution; Compensation; Background Exposure; Value of Actions; Comparison of Values. Ultimate Justification); Implementation: Ethics, Law & Economics]; Effects of Ionising Radiation in Low-Dose Range: Radiobiological Basis [What Is a Low Dose? (Microdosimetric & Biological Considerations); DNA Damage & Repair; Cellular Damages (Chromosomal Aberrations; Cell Transformation; Gene Mutations in Somatic Cells; Modifying Phenomena); Animal Experiments (Carcinogenesis & Life Shortening; Hereditary Diseases)]; Toxicology of Chemical Carcinogens [General Concepts & Dose-Response Relationships; Modifiers of Dose-Response of the Curve; Endogenous Chemical Carcinogens; Examples of Carcinogens & Modifiers Leading to Different Dose-Response Types (Vinyl Chloride; Aflatoxin B1; N,N-Diethylnitrosamine DEN; NNK (4-[N-methyl-N-nitrosoamino]-1-[3-pyridyl]-1-butanone); 2-Acetylaminofluorene 2-AAF; Arsenic; 4-Aminobiphenyl 4-ABP; Formaldehyde; Vinyl Acetate; Non DNA-Reactive Genotoxins; Non-Genotoxic Carcinogens); Interspecies Extrapolation; Interindividual Variations of Toxicological Response in Human Population (Age (Children); Relevance of Polymorphisms for Low-Dose Exposures)]; Epidemiological Perspectives on Low-Dose Exposure to Human Carcinogens [(Epidemiological Considerations & Methods; Relative & Absolute Risk Estimates; Biostatistical Considerations); Ionising & Non-Ionising Radiation (UV-light; Mobile Phones; Other Electro-Magnetic Fields); Smoking; Other Potential Carcinogenic Compounds (Insecticides; Industrial Chemicals & Waste & Emissions; Asbestos)]; Mathematical Models of Carcinogenesis [(Models of Carcinogenesis; Hazard & Excess Risk); Models Without Clonal Expansion; Models with Clonal Expansion; Ionising Radiation (Effects of Inhaled Radon Progeny; Effects of External Exposures; Low-Dose Radiobiological Effects & Risk Estimation); Carcinogenic Substances (Replication & Apoptosis of Intermediate Cells in Hepatocarcinogenesis; Combined Effects of an Initiating & Promoting Agent on Hepatocarcinogenesis; Lung Cancer Due to Coke Oven Emissions); Ionising Radiation & Carcinogenic Substances (Radon, Smoking, Arsenic; Low-Dose Risk After Exposure to an Initiating & Promoting Agent); Likelihood, Model Fits & Deviance]; Comparing Summary of Action of Ionising Radiation & Chemicals in Carcinogenesis; Hypothesis Testing & the Choice of Dose-Response Model [Uncertainties in Dose-Response Modelling (Extrapolation; Thresholds); Theories of Science (Hypothetico-Deductive Method; Laws, Hypotheses, Theories & Models: Differences Between Biology & Physics; Choosing Between Alternative Hypotheses; Popperian Falsification; Safety, Strength & Simplicity; Ad Hoc Hypothesis; Scientific Plausibility & Standards of Proof; Choice of Hypothesis in Science & for Policy]; Risk Evaluation & Communication [Risk Analysis (Definitions; Risk Assessment & Characterisation; Uncertainty, Precautionary Principle & Governance; Risk Management; Comparative Aspects of Interpreting Risks); Communication of Information on Risk]; Low Doses in Health-Related Environmental Law [Legal Framework; Risk Assessment, Low Doses & Environmental Law; Risk Assessment: Science & Law; Decision on the Tolerability of Exposure to Low Doses & Measures to Prevent or Reduce Risks; Organisation of the Decision-Making Process]; Summary; Zusammenfassung; Recommendations for Environmental Risks to Human Health: Evaluation & Regulatory Processes; Glossary].…
Seller Inventory # 004659
- Title
- Low Dose Exposures in the Environment: Dose-Effect Relations and Risk Evaluation (Ethics of Science and Technology Assessment, 23)
- Author
- Christian Streffer
- Publisher
- Springer
- Publication year
- 2004
- Condition
- Good
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 3540210830
- ISBN 13
- 9783540210832
"Synopsis" may belong to another edition of this title.
From the Back Cover
The ever-increasing release of harmful agents due to human activities have led in some areas of the world to heavy pollution. In order to protect human health and the environment, environmental standards that shall limit the release and the concentration of those toxic agents in the environment and hence the exposure to it have to be established. The related assessment and decision-making procedures have to be based on solid scientific data about the effects and mechanisms of these agents as well as on ethical, social and economic aspects. For risk evaluation, the knowledge of the dose response curve is an essential prerequisite. Dose responses without a threshold dose are most critical in this connection. Such dose responses are assumed for mutagenic and carcinogenic effects, which, therefore, dominate also the discussion in this book. In the environmentally important low dose range, risk estimation can only be achieved by extrapolation from higher doses with measurable effects. The extrapolation is accompanied with uncertainties which makes risk evaluation as well as risk communication frequently problematic. In order to ensure rational efficient and fair decisions beyond a sound scientific assessment the dialogue between disciplines, with the affected people and with the general public is necessary. In this book, the whole range of relevant and essential aspects of risk evaluation and standard setting is addressed. Starting with the ethical foundations, the sound analysis of recent scientific findings sets the frame for further reflections by theory of cognition, psychosocial sciences, and jurisprudence. The authors end up with concluding recommendations for coping with the recent problems of standard setting in the field of environmentally relevant low doses. The book is designed to a readership of scientists, legislators, administrators, and the interested public.
"About the title" may belong to another edition of this title.
killarneybooks
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