Long Range Regulation of V(D)J Recombination (Advances in Immunology): Volume 128
Published by Academic Press 2015-11-01, 2015
- Hardcover
- New
Seller: Chiron Media, Wallingford, United KingdomChiron Media
AbeBooks seller since August 2, 2010
Condition: New
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- Title
- Long Range Regulation of V(D)J Recombination (Advances in Immunology): Volume 128
- Author
- Cornelis Murre
- Publisher
- Academic Press 2015-11-01
- Publication year
- 2015
- Condition
- New
- Binding
- Hardcover
- ISBN 10
- 0128032960
- ISBN 13
- 9780128032961
Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens
As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes.
- Focuses on the generation of an effective immune response to invading pathogens
- Contains contributions from leading authorities
- Informs and updates on all the latest developments in the field of immunology
"Synopsis" may belong to another edition of this title.
About the Author
Dr. Murre has focused his research on the regulation and function of helix-loop-helix (HLH) proteins in stem cells, lymphocyte development and homeostasis. Control of tissue-specific gene expression during B and T lymphocyte development, cell growth, cell death and aging are the prominent themes in his research. Specifically the Murre laboratory has shown that subset of HLH proteins, the "E proteins", contribute to B lineage- and T lineage- specific gene expression programs, regulate lymphocyte survival and cellular proliferation, activate the rearrangement of antigen receptor genes, and control progression through critical developmental checkpoints. In more recent studies they have constructed a global network consisting of transcriptional regulators, signaling and survival factors that we propose orchestrates B cell fate. Currently, his studies are focused on physical mechanisms that underpin the generation of antigen receptor diversity.
"About the title" may belong to another edition of this title.
Chiron Media
Wallingford, United Kingdom
AbeBooks seller since August 2, 2010
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