Late-Stage Functionalization and Diversification in Organic Synthesis : Methods and Applications
Language: English
Published by Wiley-VCH Gmbh Apr 2026, 2026
- Hardcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
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Add to basketItem description from seller
Neuware - Provides a much-needed overview of the most important methods for the late-stage transformation of complex molecules, such as C-H functionalization, C-X bond activation, cross-coupling reactions, fluorination, etc.
Seller Inventory # 9783527354184
- Title
- Late-Stage Functionalization and Diversification in Organic Synthesis : Methods and Applications
- Author
- Tatiana Besset
- Publisher
- Wiley-VCH Gmbh Apr 2026
- Publication year
- 2026
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 3527354182
- ISBN 13
- 9783527354184
- Item weight
- 772 grams
- Dimensions
- 248x173x24 mm
Presents state-of-the-art strategies for the late-stage functionalization and diversity-oriented synthesis of challenging organic compounds
Late-stage functionalization (LSF) and diversity-oriented synthesis have emerged as powerful approaches in contemporary organic chemistry, enabling the selective modification of complex molecules at advanced stages of synthesis. These strategies offer unique advantages in drug discovery, medicinal chemistry, and natural product derivatization, where access to structurally diverse analogues is crucial. By allowing transformations that would otherwise require lengthy synthetic routes, LSF and diversity-oriented synthesis open pathways to molecules of high biological, pharmaceutical, and material relevance, significantly streamlining discovery processes.
Late-Stage Functionalization and Diversification in Organic Synthesis: Methods and Applications provides a comprehensive overview of the latest developments in this rapidly expanding field. Presenting both practical methodologies and mechanistic insights, the book covers transition metal catalysis, photo- and electrocatalysis, flow chemistry, and radioisotope insertion. In addition, the book:
- Places a unique focus on diversity-oriented synthesis, showcasing C-O, C-N, and C-S bond activation
- Highlights molecular editing and stereochemical editing as powerful new strategies for structural diversification
- Includes applications to natural products, pharmaceuticals, and radiopharmaceuticals
Late-Stage Functionalization and Diversification in Organic Synthesis: Methods and Applications is essential reading for graduate students, postdoctoral researchers, and professionals in organic chemistry, medicinal chemistry, and natural products research. It is particularly suited for advanced courses in organic synthesis and catalysis, and also serves as a practical reference for chemists working in the pharmaceutical and biotechnology industries.
"Synopsis" may belong to another edition of this title.
About the Author
Tatiana Besset is a CNRS Research Director at Rouen Normandy University (UMR6064 CARMeN Institute, INSA Rouen Normandy), France. Her research has been recognized by several awards and honors, including the CNRS Bronze Medal, the “SCF” Jean-Pierre Sauvage and Jean-Marie Lehn Prize, the Thieme Chemistry Journals Award, and the RSC Fluorine Prize. Elected as a Chemistry Europe Fellow in 2022, her research focuses on the development of new transition metal-catalyzed transformations, C–H bond functionalization, and innovative strategies in organofluorine chemistry.
"About the title" may belong to another edition of this title.
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