Laron Syndrome - From Man to Mouse : Lessons from Clinical and Experimental Experience

Language: English

Published by Springer Vieweg, 2016

3662501716 / 9783662501719

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Druck auf Anfrage Neuware - Printed after ordering - Laron syndrome (LS), or primary growth hormone (GH) insensitivity, was first described in 1966. Since then, many patients worldwide have been diagnosed with LS, which involves defects in the GH receptor that cause combined congenital deficiency of GH and IGF-I activities. In this comprehensive book the authors draw upon 50 years of multidisciplinary clinical and investigative follow-up of the large Israeli cohort of LS patients. The genetic basis of the syndrome is fully considered, and all aspects of the pathophysiology of IGF-I deficiency are described. Data derived from the recently generated mouse model of LS are reviewed and compared with the human LS experience. Valuable advice is provided on treatment, and treatment effects, such as metabolic effects, adipose tissue alterations, and impact on aging, are fully explored. Together, this book condenses, consolidates, compares, and contrasts data derived from the human and mouse LS experiences and provides a unique resource for clinical and basic scientists to evaluate and compare IGF-I and GH actions.

Seller Inventory # 9783662501719

Title
Laron Syndrome - From Man to Mouse : Lessons from Clinical and Experimental Experience
Author
J. Kopchick
Publisher
Springer Vieweg
Publication year
2016
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3662501716
ISBN 13
9783662501719
Item weight
1,130 grams
Dimensions
260x193x30 mm

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

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