Label-Free Biosensor Methods in Drug Discovery

Ye Fang

ISBN 10: 1493926160 / ISBN 13: 9781493926169

Published by Springer New York, Springer New York Apr 2015, 2015

About this Item

Neuware -This volume explores label-free biosensors, advantageous in part because this technology bypasses the need of labels, reporters, and cell engineering, all of which are common to labeled techniques but may introduce artifacts in assay results. Addressing several fundamental and practical aspects as to how to implement label-free methods in the drug discovery process, this book covers a wide range of topics, including binding kinetics determination, fragment screening, antibody epitope mapping, protein-protein interaction profiling and screening, receptor pathway deconvolution, drug pharmacology profiling and screening, target identification, drug toxicity assessment, and physical phenotype profiling and diagnostics based on various cellular processes such as cell adhesion, migration, invasion, infection, and inflammation. As part of the Methods in Pharmacology and Toxicology series, chapters aim to provide key detail and implementation advice to aid with progress in the lab.Practical and thorough, Label-Free Biosensor Methods in Drug Discovery provides a new avenue for rapid access to a focused collection of highly regarded contributions in the field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 404 pp. Englisch.

Seller Inventory # 9781493926169

Bibliographic Details

• Title: Label-Free Biosensor Methods in Drug Discovery
• Publisher: Springer New York, Springer New York Apr 2015
• Publication Date: 2015
• Language: English
• ISBN 10: 1493926160
• ISBN 13: 9781493926169
• Binding: Buch
• Condition: Neu
• Dimensions: 260W x 183H x 26D millimeters 260 millimeters width by 183 millimeters height by 26 millimeters depth
• Weight: 954 grams

About this title

Synopsis

This volume explores label-free biosensors, advantageous in part because this technology bypasses the need of labels, reporters, and cell engineering, all of which are common to labeled techniques but may introduce artifacts in assay results. Addressing several fundamental and practical aspects as to how to implement label-free methods in the drug discovery process, this book covers a wide range of topics, including binding kinetics determination, fragment screening, antibody epitope mapping, protein-protein interaction profiling and screening, receptor pathway deconvolution, drug pharmacology profiling and screening, target identification, drug toxicity assessment, and physical phenotype profiling and diagnostics based on various cellular processes such as cell adhesion, migration, invasion, infection, and inflammation. As part of the Methods in Pharmacology and Toxicology series, chapters aim to provide key detail and implementation advice to aid with progress in the lab.

Practical and thorough, Label-Free Biosensor Methods in Drug Discovery provides a new avenue for rapid access to a focused collection of highly regarded contributions in the field.