Jasper's Basic Mechanisms of the Epilepsies
Language: English
Published by Oxford University Press, 2024
- Hardcover
- New
Seller: PBShop.store US, Wood Dale, IL, U.S.A.PBShop.store US
AbeBooks seller since April 7, 2005
Condition: New
£ 222.55
Quantity: 14 available
Add to basketItem description from seller
Seller Inventory # FU-9780197549469
- Title
- Jasper's Basic Mechanisms of the Epilepsies
- Author
- Noebels, Jeffrey L
- Publisher
- Oxford University Press
- Publication year
- 2024
- Condition
- New
- Binding
- HRD
- Language
- English
- ISBN 10
- 0197549462
- ISBN 13
- 9780197549469
- Edition
- 5th or later Edition
- Item weight
- 6,193 grams
Jasper's Basic Mechanisms of the Epilepsies has served as the definitive reference in the field of basic research in the epilepsies for five decades through four well-regarded editions. Since its inception, the book has been an indispensable must-read and belongs in the hands of every experimental epilepsy investigator, practicing epileptologist, clinical neuroscientist, and student for both clinical and basic science reference, doctoral and board exam preparation.
This fifth edition is the most ambitious yet and remains the definitive reference in the field, providing encyclopedic and updated coverage of the current understanding of basic research in the epilepsies, while also mapping new research directions for the next decade, and reviewing how molecular laboratory evidence is now being translated into new therapeutics. In 79 chapters, the book considers the role of interactions between neurons, synapses, and glia in the initiation, spread, and arrest of seizures. It examines mechanisms of excitability, synchronization, seizure susceptibility and, ultimately, their contributions to epileptogenesis. It provides a framework for expanding the monogenic epilepsy genome and understanding the complex heredity responsible for common epilepsies. It explores the molecular and cellular disease mechanisms of ion channelopathies, developmental epilepsy genes, and progressive myoclonic epilepsies. It considers newly emerging mechanisms of epilepsy comorbidities. And, for the first time, it describes current efforts to identify biomarkers of disease progression and translate discoveries of epilepsy disease mechanisms into new therapeutic strategies at the frontier of molecular medicine.
"Synopsis" may belong to another edition of this title.
About the Author
Massimo Avoli is Professor in the Departments of Neurology & Neurosurgery and Physiology at McGill University, and a member of the Neural Circuits Research Group at the Montreal Neurological Institute-Hospital. His laboratory employs electrophysiological, pharmacological and molecular approaches to analyze the mechanisms of neuronal network excitability and seizure generation.
Michael A. Rogawski is Distinguished Professor of Neurology and Pharmacology at the University of California, Davis School of Medicine. His research encompasses the cellular neurophysiology of ion channels, the mechanisms of action of antiseizure medications, and epilepsy therapy discovery and development.
Annamaria Vezzani
is head of the Laboratory of Experimental Neurology, Department of Neuroscience at the Istituto di Ricerche Farmacologiche Mario Negri IRCCS. Her main research focus is on mechanisms of seizures and epileptogenesis, with the aim of identifying biomarkers and developing new epilepsy treatments.
Antonio V. Delgado-Escueta is Professor Emeritus in Neurology at the David Geffen School of Medicine at UCLA. He studies the mechanisms of genetic epilepsies, including Lafora progressive myoclonus epilepsy and the genetic generalized epilepsies, like Juvenile Myoclonic Epilepsies and Childhood Absence Epilepsies.
"About the title" may belong to another edition of this title.
PBShop.store US
Wood Dale, IL, U.S.A.
AbeBooks seller since April 7, 2005
Shipping rates within U.S.A.
| Item | 7 to 14 business days | 7 to 14 business days |
|---|---|---|
| First item | £ 0.00 | £ 0.00 |
Payment methods
Store description
Specialty
Hardbacks, PaperbacksSeller's business information
Pbshop.co.uk Ltd
Unit 22 Horcott Industrial Estate, Horcott Road
Fairford, United Kingdom GL7 4BX
Terms of sale
Returns Policy
We ask all customers to contact us for authorisation should they wish to return their order. Orders returned without authorisation may not be credited.
If you wish to return, please contact us within 14 days of receiving your order to obtain authorisation.
Returns requested beyond this time will not be authorised.
Our team will provide full instructions on how to return your order and once received our returns department will process your refund.
Please note the cost to return any unwanted order to us is borne by the buyer.
Should your order arrive damaged, not as advertised or faulty, we must be advised of this within 14 days of delivery. Please contact us so we can find the best solution for you.
Our Customer Care Team can be contacted via emailing paperback-us@paperbackshop.co.uk, or by calling our UK Office on +441285 712 917. We are available 9:00am till 5:30pm GMT weekdays and 9:00am till 1:00pm GMT on Saturdays.
Right of withdrawal
If you are a consumer you can withdraw from the contract in accordance with the following. Consumer means any natural person who is acting for purposes which are outside his trade, business, craft or profession.
Information regarding the right of withdrawal
Statutory right to withdraw
You have the right to withdraw from this contract within 14 days without giving any reason.
The withdrawal period will expire after 14 days from the day on which you acquire, or a third party other than the carrier and indicated by you acquires, physical possession of the last good or the last lot or piece.
To exercise the right of withdrawal, electronically fill in and submit a clear statement on our website, under "My Purchases" in "My Account". We will communicate to you an acknowledgement of receipt of such a withdrawal on a durable medium (e.g. by e-mail) without delay.
To meet the withdrawal deadline, it is sufficient for you to send your communication concerning your exercise of the right of withdrawal before the withdrawal period has expired.
Effects of withdrawal
If you withdraw from this contract, we will reimburse to you all payments received from you, including the costs of delivery (except for the supplementary costs arising if you chose a type of delivery other than the least expensive type of standard delivery offered by us).
We may make a deduction from the reimbursement for loss in value of any goods supplied, if the loss is the result of unnecessary handling by you.
We will make the reimbursement without undue delay, and not later than 14 days after the day on which we are informed about your decision to withdraw from this contract.
We will make the reimbursement using the same means of payment as you used for the initial transaction, unless you have expressly agreed otherwise; in any event, you will not incur any fees as a result of such reimbursement.
We may withhold reimbursement until we have received the goods back, or you have supplied evidence of having sent back the goods, whichever is the earliest.
You shall send back the goods or hand them over to PBShop.store US, Springfield Gardens, New York, U.S.A., +44 1285 712917, without undue delay and in any event not later than 14 days from the day on which you communicate your withdrawal from this contract to us. The deadline is met if you send back the goods before the period of 14 days has expired. You will have to bear the direct cost of returning the goods. You are only liable for any diminished value of the goods resulting from the handling other than what is necessary to establish the nature, characteristics and functioning of the goods.
Exceptions to the right of withdrawal
The right of withdrawal does not apply to:
- The delivery of newspapers, journals or magazines with the exception of subscription contracts; and
- The supply of digital content which is not supplied on a tangible medium (e.g. on a CD or DVD) if you accepted when you placed your order that we could start to deliver it, and that you could not withdraw once delivery had started.
Shipping terms
Books are shipped from our US or UK warehouses. Delivery estimates allow for delivery from either location.