Ion Channels: From Structure to Function (eng)
Language: English
Published by Oxford University Press, 2009
- Hardcover
- New

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- Title
- Ion Channels: From Structure to Function (eng)
- Author
- Kew, James
- Publisher
- Oxford University Press
- Publication year
- 2009
- Condition
- new
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 0199296758
- ISBN 13
- 9780199296750
- Item weight
- 1.73 kilograms
This book provides a comprehensive overview of ion channel structure and function. It comprises two major parts:
Part one - an introductory overview of the ion channel superfamily and the generic aspects of ion channel function. This part also reviews the methodologies by which ion channel function can be studied from the perspective of performing detailed biophysical characterisation through to the deployment of high throughput approaches for identifying novel ion channel ligands.
Part two of the book provides an in-depth review of the individual ion channel subfamilies and, as such, is subdivided into four broad sections: Voltage-Gated Ion Channels, Extracellular Ligand-Gated Ion Channels, Intracellular Ligand-Gated Ion Channels, and Polymodal-Gated Ion Channels, with each chapter therein focused on specific family members. These chapters have been written by world leading experts and provide a detailed overview of the structure, biophysics, localization, pharmacology, physiology, and disease relevance of each particular ion channel subfamily.
Reviewing both the basic principles of ion channel function and providing a detailed up-to-date review of the physiological and pharmacological aspects of individual ion channel sub-families, this book constitutes both an excellent introduction to the field for non-specialists as well as a highly valuable reference text for experienced researchers already working in the ion channel area.
"Synopsis" may belong to another edition of this title.
About the Author
Ceri Davies received BSc (Hons) and Ph.D. degrees in Pharmacology from Bristol University in 1988 and 1991. He held a Lectureship in Neuropharmacology at the University of Edinburgh until 1998 when he moved into the pharmaceutical industry running an electrophysiology team at Organon laboratories near Glasgow. During this appointment his work focussed on developing novel approaches to treat psychiatric disorders. He joined GlaxoSmithKline a year later as Head of Electrophysiology in the Neurology and Gastrointestinal Centre for Excellence in Drug Discovery (CEDD) before moving to head up the Neuropharmacology and Physiology department in the Psychiatry CEDD in 2003. Since May 2008 he has led the Synaptic Plasticity and Neural Networks Discovery Performance Unit within the newly formed Neurosciences CEDD.
"About the title" may belong to another edition of this title.
Brook Bookstore On Demand
Napoli, NA, Italy
AbeBooks seller since October 11, 2022
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