Intestinal Permeability Studies | Techniques for prediction and their application in biopharmaceutical classification of compounds

Parvin Zakeri-Milani (u. a.)

ISBN 10: 3843392277 / ISBN 13: 9783843392273

Published by LAP LAMBERT Academic Publishing, 2011

Intestinal Permeability Studies | Techniques for prediction and their application in biopharmaceutical classification of compounds | Parvin Zakeri-Milani (u. a.) | Taschenbuch | 180 S. | Englisch | 2011 | LAP LAMBERT Academic Publishing | EAN 9783843392273 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 107133367

Synopsis:

Over the recent years, interest has grown in using in-vitro and in-situ methods to predict as early as possible in-vivo oral absorption potential of a drug, to determine the mechanism and rate of transport across the intestinal mucosa and to alert the possible windows of absorption and also possible restrictions to the formulation approach. Since human in-vivo studies are not feasible, this prediction is of considerable interest at an early stage of drug development. This book is meant to provide an overview on various in-vitro and in-situ models for the study of drug transport, with an emphasis on in-situ perfusion and cell culture techniques, and data generated for each model for drugs with a broad range of physicochemical properties.

About the Author: Parvin Zakeri-Milani: PharmD, PhD, Faculty of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Hadi Valizadeh: PharmD, PhD, Faculty of Pharmacy and Pharmaceutical Nanotechnology Research Center,Tabriz University of Medical Sciences. Hosnieh Tajerzadeh: PharmD, PhD, Tehran University of Medical Sciences.

Bibliographic Details

Title: Intestinal Permeability Studies | Techniques...
Publisher: LAP LAMBERT Academic Publishing
Publication Date: 2011
Binding: Taschenbuch
Condition: Neu