Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
Language: English
Published by Springer, Springer Mai 2013, 2013
- Softcover
- New
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000
AbeBooks seller since January 23, 2017
Condition: New
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This item is printed on demand - Print on Demand Titel. Neuware -Rationale for the Effective Use of Pharmacokinetics and Pharmacodynamics in Early Drug Development.- The Case for Preclinical Pharmacodynamics.- Utility of Kinetic, Dynamic, and Metabolic Data in Nonclinical Pharmacology/Toxicology Studies.- Preclinical Pharmacokinetic & Pharmacodynamic Studies.- Pharmacokinetics and Drug Metabolism in Animal Studies (ADME, Protein Binding, Mass Balance, Animal Models).- Nonclinical Considerations: Disposition of Drugs.- Use of Acute Toxicity Data in the Design and Interpretation of Subchronic and Chronic Toxicity Studies.- Use of Pharmacokinetics and Pharmacodynamics in Preclinical Studies to Guide Dosage Escalation Schemes in Phase I Studies of Anticancer Drugs.- Use of Toxicokinetic Principles in Drug Development: Bridging Preclinical and Clinical Studies.- Methodology for Preclinical Pharmacodynamic Studies.- Preclinical Pharmacodynamics of Central Nervous System Active Agents.- Preclinical Pharmacodynamics of Antihypertensives.- Preclinical Pharmacodynamics of Anxiolytics: Effects of Chronic Benzodiazepine Administration.- Guidelines for Development of a New Diuretic Agent.- Preclinical Pharmacodynamics of Anti-Inflammatory Drugs.- Preclinical & Clinical Pharmacokinetics.- The Role of Pharmacokinetics in the Drug Development Process.- Implementation of an Effective Pharmacokinetics Research Program in Industry.- Pharmacoepidemiology, Population Pharmacokinetics and New Drug Development.- Assessment of Pharmacokinetic Drug Interactions in Clinical Drug Development.- Clinical Pharmacodynamics.- Pharmacokinetic/Pharmacodynamic Models and Methods.- Pharmacokinetic and Pharmacodynamic Modeling Applied to Anesthetic Drugs.- Pharmacodynamic/Pharmacokinetic Relationships for Rapidly Acting Drugs (NSAIDS) in Rheumatoid Arthritis: Problems and Preliminary Solutions.- The Value of Plasma-Warfarin Measurement.- Clinical Pharmacodynamics of Cardiovascular Agents: Focus on Sudden Cardiac Death.- The Benzodiazepines: Kinetic-Dynamic Relationships.- Application of Pharmacodynamics & Pharmacokinetics in the Drug Development Process.- The Integration of Pharmacodynamics and Pharmacokinetics in Rational Drug Development.- Concentration-Controlled Trials: Basic Concepts, Design, and Implementation.- Summary Report.- Opportunities for Integration of Pharmacokinetics, Pharmacodynamics and Toxicokinetics in Rational Drug Development.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 288 pp. Englisch. …
Seller Inventory # 9781475715224
- Title
- Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
- Author
- A. Yacobi
- Publisher
- Springer, Springer Mai 2013
- Publication year
- 2013
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 1475715226
- ISBN 13
- 9781475715224
- Item weight
- 502 grams
- Dimensions
- 244x170x16 mm
"Synopsis" may belong to another edition of this title.
buchversandmimpf2000
Emtmannsberg, BAYE, Germany
AbeBooks seller since January 23, 2017
Shipping rates from Germany to U.S.A.
| Item | 60 to 60 business days | 60 to 60 business days |
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| First item | £ 51.39 | £ 64.23 |
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