Inorganic Polyphosphates: From Basic Research to Medical Application. This item is unavailable.
Language: English
Published by Springer, 2023
- Softcover
- Used
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- Title
- Inorganic Polyphosphates: From Basic Research to Medical Application
- Author
- MÜller, Werner E. G.
- Publisher
- Springer
- Publication year
- 2023
- Condition
- As New
- Binding
- Soft cover
- Language
- English
- ISBN 10
- 3031012399
- ISBN 13
- 9783031012396
This volume focuses on the biomedical aspects of inorganic polyphosphates, a family of unique bio-inorganic polymers.
In recent years, great advances have been made in understanding the development, metabolism, and physiological role of inorganic polyphosphates. These energy-rich polymers, which consist of long chains of phosphate units, are evolutionary old molecules. The acidocalcisomes, conserved organelles from bacteria to humans, as well as the mitochondria play a central role in polyphosphate production and storage. Polyphosphates have been assigned multiple functions, some of which are closely related to medically important processes, such as blood coagulation and fibrinolysis, energy metabolism, cell cycle regulation, apoptosis, chaperon function, microvascularization, stress response, neurodegeneration and aging. The development of bioinspired polyphosphate particles, in combination with suitable hydrogel-forming polymers enabled the development of new strategies in regenerative medicine, in particular for hard and soft tissue repair, but also in drug delivery and antimicrobial defense.
This book not only highlights the basic research in this area, but also discusses possible applications. Therefore, it appeals to scientists working in cell biology, biochemistry, and biomedicine and practicioners alike.
"Synopsis" may belong to another edition of this title.
About the Author
Xiaohong Wang is a chemist and material scientist. In 2005 she became a professor in inorganic chemistry. She has a long-standing expertise in the development and characterization of regenerative-active materials and the molecular processes underlying their biological/morphogenetic activity. Since 2006 she has been working together with W.E.G. Müller’s group and she joined his group in 2009. Her scientific work (more than 200 peer-reviewed publications, Hirsch h-index: 41 [ISI-WOS]) was supported by several grants, as the coordinator or a PI, including four EU-funded projects (Core-Shell, SPECIAL, MarBioTec, and H2020 InnovaConcrete), and grants from the German Ministry of Research, like the ongoing SKIN-ENERGY project on wound healing. In addition, she is scientific coordinator of the German-Chinese Joint Center for Bioinspired Materials.
"About the title" may belong to another edition of this title.