Immunodeficiency in HIV Infection And AIDS

Janossy, G., Autran, B., Miedema, F.

ISBN 10: 3805555474 ISBN 13: 9783805555470
Published by S Karger Pub, 1992
Used Hardcover

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Synopsis:

As a contribution to the controversy about AIDS development, this volume identifies HIV infection associated with CD4 depletion as the primary cause, severely aggravated by secondary immunological disorders, which are described. The book provides a comprehensive review of cellular immune defects associated with HIV infection as well as of immunological assays and parameters useful for the routine evaluation of immune deficiencies. Authored by researchers from leading institutions with the longest follow-up of HIV-1 infected patients in Europe and the USA, the articles summarize both the normal ranges of immune parameters and their changes during the various stages of HIV disease. The first section of the book focuses on the clinical use of CD4 lymphocyte counts as the best surrogate marker available so far for guiding the laboratory assessment of AIDS progression. A further section concentrates on defects of lymphocyte proliferation and specific immunity in asymptomatic HIV-positive patients. The final section deals with recent advances in understanding the functional immunopathology of AIDS.

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Bibliographic Details

Title: Immunodeficiency in HIV Infection And AIDS
Publisher: S Karger Pub
Publication Date: 1992
Binding: Hardcover
Condition: Good

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