The Immune Synapse as a Novel Target for Therapy (Progress in Inflammation Research Series)
Language: English
Published by Birkhauser, Switzerland, 2007
- Hardcover
- Used
Seller: The Book Exchange, Macclesfield, Cheshire, United KingdomThe Book Exchange
AbeBooks seller since December 12, 2003
Condition: Used - Near fine
£ 28.85
Quantity: 1 available
Add to basketItem description from seller
9783764382957. Pictorial board hardcover, from closed pharmaceutical company library. 196 pages, index, illustrated with charts, tables and diagrams. An overview on the progress in immune synapse research, from basic science to clinical trials, and the major mechanisms involved. Discusses how interfering with T cell activation may lead to immune tolerance, immune modulation, and the recruitment of regulatory T cells; the role of monoclonal antibodies in tolerance induction; and mechanisms maintaining dominant tolerance. Contents as new, clean, tight and bright.
Seller Inventory # 029530
- Title
- The Immune Synapse as a Novel Target for Therapy (Progress in Inflammation Research Series)
- Author
- Luis Graca
- Publisher
- Birkhauser, Switzerland
- Publication year
- 2007
- Condition
- Near Fine
- Book Type
- Book
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 3764382953
- ISBN 13
- 9783764382957
- Seller catalogs
- Medical Research
"Synopsis" may belong to another edition of this title.
From the Back Cover
The immune synapse can be compared to a molecular machine that controls T cell activation when getting in contact with an antigen-presenting cell (APC). The immune synapse is involved in the transfer of information across the T cell–APC junction. It plays an essential role in the control and nature of the immune response.
In recent years several approaches have been developed to reprogram the immune response by targeting molecules involved in the immune synapse. Monoclonal antibodies, such as those targeting the lymphocyte co-receptor, costimulatory and adhesion molecules (CD3, CD4, CD40L, CTLA4-Ig, LFA-1), or altered peptide ligands have been shown capable of inducing immune tolerance in transplantation, autoimmunity and allergy.
This volume discusses the progress in the field, from basic science to clinical trials, and the major mechanisms involved. It is of interest to clinicians and researchers working in this area.
"About the title" may belong to another edition of this title.
The Book Exchange
Macclesfield, Cheshire, United Kingdom
AbeBooks seller since December 12, 2003
Shipping rates from United Kingdom to U.S.A.
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