IHC PROFILING OF CYTOKERATIN 8 AND CYTOKERATIN 18 IN ORAL CANCER
Language: English
Published by LAP LAMBERT Academic Publishing, 2010
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 47.68
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Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - The expression of simple epithelial cytokeratins 8 and 18 is normally seen in the embryonic cells and lost in adult squamous epithelium. CK 8 and 18 play a role in tumor progression and metastatic potential as these are expressed only in the poorly differentiated and not in well differentiated squamous cell carcinomas. It appears that increased expression of the embryonic or simple epithelial cytokeratins 8 and 18 in some way changes the phenotypic characteristics of stratified epithelial cells, resulting in malignant transformation. Presence of Cytokeratin 8 and 18 in poorly differentiated foci of Oral squamous cell carcinoma even in the absence of metastasis could indicate a poor prognosis in these patients. However they are of functional importance in malignancy of keratinocytes and could be related to tumor invasion and/or to changes in epithelial mesenchymal interactions.
Seller Inventory # 9783843352178
- Title
- IHC PROFILING OF CYTOKERATIN 8 AND CYTOKERATIN 18 IN ORAL CANCER
- Author
- Shankargouda Patil
- Publisher
- LAP LAMBERT Academic Publishing
- Publication year
- 2010
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3843352178
- ISBN 13
- 9783843352178
- Item weight
- 179 grams
- Dimensions
- 220x150x8 mm
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|---|---|---|
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