Hydrophilic Polymers
Language: English
Published by LAP LAMBERT Academic Publishing Okt 2014, 2014
- Softcover
- New
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000
AbeBooks seller since January 23, 2017
Condition: New
£ 48.56
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Add to basketItem description from seller
This item is printed on demand - Print on Demand Titel. Neuware -The objective of present work was to check the effect of hydrophilic polymers on the release of Clozapine from matrix tablet. Hydrophilic polymers were used to control the release of drug. Matrix tablets were prepared using direct compression method. HPMC K 100 M, Guar gum and Sodium CMC used as release retardant polymers. Polymers were used in the ratio of 1:3, 1:4, 1:5 and 1:8. Rate of drug release decreased as the polymer ratio increased. The level of polymer ratio also had an effect on swelling index showing a linear relationship. At 1:8 (drug: polymer) ratio with HPMC K 100 M, tablets showed desirable release pattern, release up to 24 hr. It was found to release the drug in Zero order up to 24 hrs. For further study, 1:8 (drug: polymer) ratio was evaluated with particle sizes ranging from 250 micron to 106 microns on the release of drug. It was observed that as the particle size decreases, release also retards but follows zero order kinetics.Books on Demand GmbH, Überseering 33, 22297 Hamburg 100 pp. Englisch.…
Seller Inventory # 9783659624063
- Title
- Hydrophilic Polymers
- Author
- Gunvant Patel
- Publisher
- LAP LAMBERT Academic Publishing Okt 2014
- Publication year
- 2014
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3659624063
- ISBN 13
- 9783659624063
- Item weight
- 167 grams
- Dimensions
- 220x150x6 mm
"Synopsis" may belong to another edition of this title.
buchversandmimpf2000
Emtmannsberg, BAYE, Germany
AbeBooks seller since January 23, 2017
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| Item | 60 to 60 business days | 60 to 60 business days |
|---|---|---|
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