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During the two decades since the publication of the first edition of Histological Typing of Bone Tumours, new methods of diagnosis, es- pecially radiological imaging techniques (computed tomography and magnetic resonance imaging), associated with advances in the new cytomorphological methods including immunohistochemistry, DNA ploidy analysis, cytogenetic chromosomal investigation, etc., have greatly improved our diagnostic tools and treatment results. These advances are reflected by the publication of new editions of various important textbooks in recent years. In these publications classifica- tion criteria differed. In contrast, the WHO classification has been relatively unaltered, and has introduced a limited number of new entities and subdivided others because of distinct histological features and biological be- haviour. In general the framework and the concept of the original classifi- cation, as it has been widely accepted, remains essentially unchanged. The classification is based on the line of histological differentiation, in many instances reflecting the type of intercellular matrix material produced. This approach is justified because it avoids theoretical his- togenetic controversies.
Synopsis: The new edition of this text reflects advances in the diagnosis and classification of bone tumours made over the 20 years since the first edition appeared. Although still based on light microscopy, the revised classification includes immunohistochemical and molecular biological findings.
Title: Histological Typing of Bone Tumours (WHO. ...
Publisher: Springer
Publication Date: 1993
Binding: Soft cover
Condition: New
Edition: 2nd Edition