High-Dimensional Data Analysis in Cancer Research

Language: English

Published by Springer, Springer Nov 2010, 2010

1441924140 / 9781441924148

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This item is printed on demand - Print on Demand Titel. Neuware -Multivariate analysis is a mainstay of statistical tools in the analysis of biomedical data. It concerns with associating data matrices of n rows by p columns, with rows representing samples (or patients) and columns attributes of samples, to some response variables, e.g., patients outcome. Classically, the sample size n is much larger than p, the number of variables. The properties of statistical models have been mostly discussed under the assumption of fixed p and infinite n. The advance of biological sciences and technologies has revolutionized the process of investigations of cancer. The biomedical data collection has become more automatic and more extensive. We are in the era of p as a large fraction of n, and even much larger than n. Take proteomics as an example. Although proteomic techniques have been researched and developed for many decades to identify proteins or peptides uniquely associated with a given disease state, until recently this has been mostly a laborious process, carried out one protein at a time. The advent of high throughput proteome-wide technologies such as liquid chromatography-tandem mass spectroscopy make it possible to generate proteomic signatures that facilitate rapid development of new strategies for proteomics-based detection of disease. This poses new challenges and calls for scalable solutions to the analysis of such high dimensional data. In this volume, we will present the systematic and analytical approaches and strategies from both biostatistics and bioinformatics to the analysis of correlated and high-dimensional data.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 168 pp. Englisch.

Seller Inventory # 9781441924148

Title
High-Dimensional Data Analysis in Cancer Research
Author
Xiaochun Li
Publisher
Springer, Springer Nov 2010
Publication year
2010
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1441924140
ISBN 13
9781441924148
Item weight
265 grams
Dimensions
235x155x10 mm

buchversandmimpf2000

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