Hepatitis B virus

Language: English

Published by Eliva Press Sep 2026, 2026

9999353088 / 9789999353083

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Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

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Softcover

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This item is printed on demand - Print on Demand Titel. Neuware -This book provides a comprehensive exploration of Hepatitis B virus (HBV) genomics, focusing on the molecular architecture and diagnostic significance of the S gene. It examines the structural properties of viral surface envelope proteins, the mechanism of viral entry via the NTCP host receptor, and the dynamics of episomal cccDNA transcription. Furthermore, the chapters present a detailed analysis of codon usage bias (CUB) across 146 HBV Genotype D transcripts, evaluating key parameters such as the Effective Number of Codons (ENc), Codon Adaptation Index (CAI), Relative Synonymous Codon Usage (RSCU), and relative dinucleotide abundance. The text investigates the evolutionary forces governing codon preferences, highlighting the dominance of natural selection over mutational pressure, CpG dinucleotide suppression for immune evasion, and the role of programmatic rare codon pausing in co-translational protein folding. Finally, the book evaluates host-pathogen adaptation by comparing HBV codon selection with human tRNA isotype profiles, offering insights into viral translational efficiency and host metabolic balance. Key Features: Provides a thorough exploration of Hepatitis B virus biology, from molecular structure to advanced genomic analysis. Presents detailed analyses of nucleotide composition, codon usage bias, and dinucleotide frequency across HBV Genotype D S gene transcripts. Discusses the diagnostic and clinical significance of the HBsAg 'a' determinant and quantitative surface antigen metrics. Introduces evolutionary models including Neutrality plots, Parity Rule 2 (PR2) bias analysis, and ENc-GC3 distributions to delineate mutational and natural selection pressures. Examines host adaptation strategies and tRNA pool alignment to understand viral translational efficiency and immune evasion mechanisms. Toward the end, the book covers the impact of host restriction factors, post-transcriptional tRNA modifications, and translational pausing on viral envelope protein synthesis. 58 pp. Englisch. …

Seller Inventory # 9789999353083

Title
Hepatitis B virus
Author
Rekha Khandia
Publisher
Eliva Press Sep 2026
Publication year
2026
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
9999353088
ISBN 13
9789999353083
Item weight
100 grams
Dimensions
229x152x4 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

5-star seller

AbeBooks seller since January 23, 2017

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Impressum Thorsten Retsch Buchversand Mimpf2000 Oberölschnitz 16 95517 Emtmannsberg Deutschland Telefon: 09209-2023188 Email: mimpf2000@online.de USt-ID-Nr.: DE 235096871 Wir führen gebrauchte Bücher aus allen Sparten der Literatur

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