Handbook of Statistical Methods for Randomized Controlled Trials
Language: English
Published by Chapman And Hall/CRC Sep 2023, 2023
Series: Book 24 of 27 - Chapman & Hall/CRC Handbooks of Modern Statistical Methods
- Softcover
- New
Seller: Books-by-Floh, Paderborn, GermanyBooks-by-Floh
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Neuware -This handbook is intended to serve as a reference text on statistical methods for randomized controlled trials. It can be used as a textbook for a graduate course in statistical methods for randomized controlled trials as well as a reference for those involved in the design, monitoring and analysis of randomized controlled trials. 656 pp. Englisch.
Seller Inventory # 9781032009100
- Title
- Handbook of Statistical Methods for Randomized Controlled Trials
- Author
- Frank Bretz
- Publisher
- Chapman And Hall/CRC Sep 2023
- Publication year
- 2023
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 1032009101
- ISBN 13
- 9781032009100
- Item weight
- 1,214 grams
- Dimensions
- 254x178x36 mm
- Series
- Book 24 of 27: Chapman & Hall/CRC Handbooks of Modern Statistical Methods
Statistical concepts provide scientific framework in experimental studies, including randomized controlled trials. In order to design, monitor, analyze and draw conclusions scientifically from such clinical trials, clinical investigators and statisticians should have a firm grasp of the requisite statistical concepts. The Handbook of Statistical Methods for Randomized Controlled Trials presents these statistical concepts in a logical sequence from beginning to end and can be used as a textbook in a course or as a reference on statistical methods for randomized controlled trials.
Part I provides a brief historical background on modern randomized controlled trials and introduces statistical concepts central to planning, monitoring and analysis of randomized controlled trials. Part II describes statistical methods for analysis of different types of outcomes and the associated statistical distributions used in testing the statistical hypotheses regarding the clinical questions. Part III describes some of the most used experimental designs for randomized controlled trials including the sample size estimation necessary in planning. Part IV describe statistical methods used in interim analysis for monitoring of efficacy and safety data. Part V describe important issues in statistical analyses such as multiple testing, subgroup analysis, competing risks and joint models for longitudinal markers and clinical outcomes. Part VI addresses selected miscellaneous topics in design and analysis including multiple assignment randomization trials, analysis of safety outcomes, non-inferiority trials, incorporating historical data, and validation of surrogate outcomes.
"Synopsis" may belong to another edition of this title.
About the Author
KyungMann Kim is Professor of Biostatistics and Statistics and Director of Clinical Trials Program, Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison. He is a former associate editor of Biometrics and an elected Fellow of the American Statistical Association, the Society for Clinical Trials, and the American Association for Advancement of Science.
Frank Bretz is a Distinguished Quantitative Research Scientist at Novartis. He is also an Adjunct Professor at the Hannover Medical School (Germany) and the Medical University Vienna (Austria). He is a former editor-in-chief of Statistics in Biopharmaceutical Research. a Fellow of the American Statistical Association, and a recipient of the Susanne-Dahms-Medal from the German Region of the International Biometric Society.
Ying Kuen (Ken) Cheung is Professor of Biostatistics and Associate Dean for Faculty in the Mailman School of Public Health at Columbia University. He is a recipient of the IBM Faculty Award on Big Data and Analytics. He is a Fellow of the American Statistical Association and a Fellow of the New York Academy of Medicine.
Lisa Hampson is a Director in Statistical Methodology at Novartis.
"About the title" may belong to another edition of this title.
Books-by-Floh
Paderborn, Germany
AbeBooks seller since March 13, 2026
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Books-by-Floh steht für ein breites, kuratiertes Buchsortiment aus einer Hand. Unser Fokus liegt auf Qualität, Vielfalt und zuverlässiger Abwicklung.
Wir führen Romane, Krimis, Thriller, Liebesromane, Lyrik, Anthologien, Mythologie, Fachbücher sowie Werke der Gegenwartsliteratur – für Leserinnen und Leser mit Anspruch.
Alle Artikel werden ausschließlich aus Deutschland versendet. Das garantiert kurze Lieferzeiten, transparente Prozesse und einen verlässlichen Service.
Unser Anspruch: unkomplizierter Einkauf, Bücher, die man gerne liest – heute und morgen.
Books-by-Floh – Bücher. Klar. Verlässlich.
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