Handbook of Molecular Force Spectroscopy

Language: English

Published by Springer US, Springer New York Dez 2007, 2007

0387499873 / 9780387499871

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This item is printed on demand - Print on Demand Titel. Neuware -Modern materials science and biophysics has increasingly focused on studying and controlling intermolecular interactions on the single-molecule level. The peer-reviewed literature contains an increasing number of studies that either measure the interaction forces directly or use mechanical forces to deform the molecules or trigger structural transitions. Molecular force spectroscopy is the result of unprecedented advances in the capabilities of modern force measurement instruments in the past decade and describes a number of techniques that use mechanical force measurements to study interactions between single molecules and molecular assemblies in chemical and biological systems. Examples of these techniques include atomic force microscopy, optical tweezers, surface forces apparatus, and magnetic tweezers. These techniques typically target a specific range of experimental systems and geometries, but all use mechanical force transducers to apply and detect nanonewton range forces between single molecules in condensed phases.Molecular force spectroscopy measurements have been very important for studies of adhesion and friction forces, where they provided the first truly nanoscale capabilities. Force spectroscopy has been instrumental in understanding mechanical properties and nanoscale dynamics of polymer systems from elasticity to nanoscale phase segregation. In biophysics, applications range from probing protein folding to direct mapping of intermolecular interaction potentials. This volume presents a review of modern force spectroscopy, including fundamentals of intermolecular forces, technical aspects of the force measurements, and practical applications. The Handbook begins with a review of fundamental physics of loading single and multiple chemical bonds on the nanometer scale with a discussion of thermodynamic and kinetic models of binding forces and dissipation effects in nanoscale molecular contacts, covers practical aspects of modern single-molecule level techniques, and concludes with applications of force spectroscopy to chemical and biological processes. Computer modeling of force spectroscopy experiments is addressed as well. In sum, Handbook of Molecular Force Spectroscopy is a comprehensive, authoritative guide to planning, understanding, and analyzing modern molecular force spectroscopy experiments with an emphasis on biophysical research.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 320 pp. Englisch.…

Seller Inventory # 9780387499871

Title
Handbook of Molecular Force Spectroscopy
Author
Aleksandr Noy
Publisher
Springer US, Springer New York Dez 2007
Publication year
2007
Condition
Neu
Binding
Buch
Language
English
ISBN 10
0387499873
ISBN 13
9780387499871
Item weight
801 grams
Dimensions
260x183x22 mm

buchversandmimpf2000

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