Guide to Techniques in Mouse Development: Mice, Embryos, and Cells: Vol 476

Wassarman, Paul (Editor)/ Soriano, Philippe M. (Editor)

ISBN 10: 0123747759 / ISBN 13: 9780123747754

Published by Academic Pr, 2010

About this Item

2nd edition. 536 pages. 9.25x6.25x1.25 inches. In Stock.

Seller Inventory # __0123747759

Bibliographic Details

• Title: Guide to Techniques in Mouse Development: Mice, Embryos, and Cells: Vol 476
• Publisher: Academic Pr
• Publication Date: 2010
• Language: English
• ISBN 10: 0123747759
• ISBN 13: 9780123747754
• Binding: Hardcover
• Condition: Brand New

About this title

Synopsis

Guide to Techniques in Mouse Development, Part A comprehensively covers new technologies and methodologies that have appeared for the study of mouse development.

• Update of volume 225 of Methods in Enzymology, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993
• Covers new technologies and methodologies, including:
• new techniques for the cryopreservation of gametes and embryos
• production of transgenic and null (knockout) animals (use of ES cells)
• generation of conditional/inducible mutant animals
• use of gene-trap mutagenesis
• analysis of allele-specific expresion
• use of new reporter constructs
• humanizing of transgenic animals
• transcript profiling of mouse development
• imaging of mouse development
• rederivation of animals and use of mouse genomics

About the Author

Philippe Soriano,is Professor of Cell, Developmental & Regenerative Biology and Professor of Oncological Sciences, Icahn School of Medicine at Mount Sinai, NY, USA