Glutamate and ATP at the Interface of Metabolism and Signaling in the Brain
Language: English
Published by Springer International Publishing, 2014
- Hardcover
- New
Condition: New
£ 80.14
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Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Suitable for advanced and graduate courses on the roles of glutamate and ATP in metabolism and signalingOnly current book on this highly researched topicContributions from leading experts in cell metabolism, intracellular signaling and neur.
Seller Inventory # 4498314
- Title
- Glutamate and ATP at the Interface of Metabolism and Signaling in the Brain
- Author
- Parpura, Vladimir|Schousboe, Arne|Verkhratsky, Alexei
- Publisher
- Springer International Publishing
- Publication year
- 2014
- Condition
- New
- Binding
- Gebunden
- Language
- English
- ISBN 10
- 3319088939
- ISBN 13
- 9783319088938
- Series
- Book 11 of 39: Advances in Neurobiology
- Seller catalogs
- Mathematik/Naturwissenschaften/Technik/Medizin
ATP acts as main energy source and is pivotal for numerous signaling cascades both inside the cells (by fuelling various transport systems and donating phosphate groups) and between the cells (by chemical transmission). Similarly glutamate acts as an important molecule for both intercellular signaling though glutamatergic transmission and cell energetics by contributing to ATP production.
In this collection of chapters, written by the leading experts in the field of cell metabolism and energetics, intracellular signaling and neurotransmission we covered various aspects of the interfacing between these two fundamental molecules. This book will be particularly useful for researchers, students, physicians and psychotherapists working in the field of neurobiology, neurology and psychiatry."Synopsis" may belong to another edition of this title.
From the Back Cover
ATP was naturally selected very early on as the main source of biological energy, and thus became an indispensable feature of life on the Earth. This was a critical evolutionary choice because it shaped enzymatic systems to utilize ATP in energy-dependent reactions and necessitated an appearance of the universal intracellular signaling system based on calcium ions; keeping cytosolic Ca2+ extremely low became vitally important, since otherwise insoluble Ca2+-phosphates would preclude the cell energetics. Thus, all living cells on the Earth, beginning from the most primitive ones, had high cytosolic concentrations of ATP and there is little surprise that ATP was soon utilized by nature for another fundamental function of sending information from one living cell to another. In summary, ATP acts as the main energy source and is pivotal for numerous signaling cascades both inside (by fueling various transport systems and donating phosphate groups) and between the cells (by chemical transmission). Similarly, glutamate acts as an important molecule for both intercellular signaling through glutamatergic transmission and cell energetics by contributing to ATP production.
In this collection of chapters, written by the leading experts in the fields of cell metabolism and energetics, intracellular signaling and neurotransmission, we covered various aspects of the interfacing between these two fundamental molecules. This book will be particularly useful for researchers, students, physicians and psychotherapists working in the field of neurobiology, neurology and psychiatry.
"About the title" may belong to another edition of this title.
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