Genomic Imprinting : Methods and Protocols

Language: English

Published by Humana, 2010

1617371645 / 9781617371646

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nach der Bestellung gedruckt Neuware - Printed after ordering - Genomic imprinting is the process by which gene activity is regulated according to parent of origin. Usually, this means that either the maternally inherited or the paternally inherited allele of a gene is expressed while the opposite allele is repressed. The phenomenon is largely restricted to mammals and flowering plants and was first recognized at the level of whole genomes. Nuclear transplantation experiments carried out in mice in the late 1970s established the non-equivalence of the maternal and paternal genomes in mammals, and a similar conclusion was drawn from studies of interploidy crosses of flowering plants that extend back to at least the 1930s. Further mouse genetic studies, involving animals carrying balanced translocations (reviewed in Chapter 3), indicated that imprinted genes were likely to be widely scattered and would form a minority within the mammalian genome. The first imprinted genes were identified in the early 1990s; over forty are now known in mammals and the list continues steadily to expand.

Seller Inventory # 9781617371646

Title
Genomic Imprinting : Methods and Protocols
Author
Andrew Ward
Publisher
Humana
Publication year
2010
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1617371645
ISBN 13
9781617371646
Item weight
664 grams
Dimensions
235x155x25 mm

AHA-BUCH GmbH

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