Gene expression during carcinogenesis: A bioinformatics perspective : An analysis of the global patterns of changes in the gene expression associated with genesis of cancer

Language: English

Published by LAP LAMBERT Academic Publishing, 2010

3838350898 / 9783838350899

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Cancer arises from a stepwise accumulation of genetic changes through expansion of the malignant cell clones in the population of pre-malignant cells undergoing Darwinian selection process. In other words, cancer is an outcome of continuous and random acquisition of the changes in the genomes of individual cells. These modifications gradually and progressively change the phenotype of the normal cell making it more malignant through a loss of an overall stability of genome. The book summarizes bioinformatic methods to analyze the most general features of the malignant cell investigating molecular phenomena common for all tumor cells, with no regard to the characteristics related to tumor s tissue of origin. The results obtained in three independent modules of the book enhance a general understanding of cancer as an expression system comprising of the components dynamically interacting with each other. These results along with novel tools for in silico analysis of the cancer cell described in the book provide novel avenues for the functional genomics and systems biology of cancer and may be of help for large-scale computational modeling of cancer.…

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Title
Gene expression during carcinogenesis: A bioinformatics perspective : An analysis of the global patterns of changes in the gene expression associated with genesis of cancer
Author
Ancha Baranova
Publisher
LAP LAMBERT Academic Publishing
Publication year
2010
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3838350898
ISBN 13
9783838350899
Item weight
340 grams
Dimensions
220x150x14 mm

AHA-BUCH GmbH

Einbeck, Germany

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