Gene Therapy for Cancer
Language: English
Published by Humana Press, Humana Press Feb 2007, 2007
Series: Book 33 of 96 - Cancer Drug Discovery and Development
- Hardcover
- New
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000
AbeBooks seller since January 23, 2017
Condition: New
£ 189.19
Quantity: 1 available
Add to basketItem description from seller
This item is printed on demand - Print on Demand Titel. Neuware -The possibility of treating cancer, a disease defined by genetic defects, by introducing genes targeting these very alterations has led to an immense interest in gene therapy for cancer. Although incremental successes have been realized, enthusiasm for gene therapy has declined due to an increasing number of obstacles. These obstacles include vector systems that do not reach systemic metastases, therapeutic genes with redundant mec- nisms allowing for cellular resistance, and toxicities in clinical trials leading to premature closure of these studies. Different tactics to overcome or circumvent these obstacles have catalyzed the development of a wide range of gene therapy approaches. Thus far, almost two-thirds of gene therapy trials have focused on cancer. This reflects the concept that gene therapy approaches for the treatment of cancer do not necessarily require long-term expression of the gene as is necessary for the treatment of primary genetic defects like hemophilia or juvenile diabetes. Unlike the treatment of genetic defects, where expr- sion of the corrected gene needs to be strong, permanent and, sometimes regulated, tactics to treat tumors can be based on temporary and locally limited effects. In addition, cancer cells have different properties than normal cells and this allows for targeting gene therapy to specific cells, a major advantage over current antitumor therapies, which are also toxic to normal cells and tissues.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 484 pp. Englisch.…
Seller Inventory # 9781588294722
- Title
- Gene Therapy for Cancer
- Author
- Kelly K. Hunt
- Publisher
- Humana Press, Humana Press Feb 2007
- Publication year
- 2007
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 1588294722
- ISBN 13
- 9781588294722
- Item weight
- 1,209 grams
- Dimensions
- 260x183x35 mm
- Series
- Book 33 of 96: Cancer Drug Discovery and Development
"Synopsis" may belong to another edition of this title.
Review
From the reviews:
"The book is divided into 3 sections. ... this book is informative and provides a comprehensive review of the advances and limitations of cancer gene therapy. ... Overall, the book provides enjoyable and instructive reading material. I highly recommend this book to scientists as well as clinicians as a reference source for cancer gene therapy. Readers would benefit from this excellent reading material, whether they are relatively new to this subspecialty or are actively working within the field of cancer gene therapy." (Prem Seth, JAMA, Vol. 299 (11), 2008)
"Gene Therapy for Cancer ... covers the current technologies of cancer gene therapy as well as the difficult task of applying these in clinical trials. ... The book also benefits through its helpful tables, drawings and illustrations. ... Gene Therapy for Cancer provides a good overview of currently available techniques for cancer gene therapy and their limitations and potential for clinical applications. The book is a useful addition to the library of both researchers and clinicians working in the field." (S. Schepelmann and C. J. Springer, British Journal of Cancer, Vol. 98 (3), 2008)
“This new volume in Humana’s series is written for oncologists, hematologists, cancer researchers, geneticists.” (Tumori, Vol. 93, 2007)
"About the title" may belong to another edition of this title.
buchversandmimpf2000
Emtmannsberg, BAYE, Germany
AbeBooks seller since January 23, 2017
Shipping rates from Germany to U.S.A.
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Impressum Thorsten Retsch Buchversand Mimpf2000 Oberölschnitz 16 95517 Emtmannsberg Deutschland Telefon: 09209-2023188 Email: mimpf2000@online.de USt-ID-Nr.: DE 235096871 Wir führen gebrauchte Bücher aus allen Sparten der Literatur
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