Gap Junctions in the Nervous System

Language: English

Published by Springer, Berlin, Springer Berlin Heidelberg, Springer, 2013

3662219379 / 9783662219379

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Druck auf Anfrage Neuware - Printed after ordering - A Cytoplasm Connexon or Hemichannel Cytoplasm external loop I - P. M. N-Termlnus Fig. 1. 1. Topology of gap junction channels. (A) Cap junction channels, extending from the cytoplasm of one cell to the cytoplasm of another, are formed by two connexons or hemichannels connected across extracellular space. (B) Each connexon is formed from six connexin subunits, each having four membrane-spanning domains and both amino and carboxyl termini within the cytoplasm. External/oops (I and II} are believed to provide the high affinity interactions between the hemichannels. 4 Gap }unctions in the Nervous System P-region of voltage sensitive nonjunctional molecules; these contributed disulfide 9 channels. And Delmar's group has ob bridges are presumably involved in intra tained evidence that intracellular acidifi connexin and inter-EL loop tertiary struc cation may result in a conformational ture. An old observation that should be change analogous to the ball and chain repeated stoichiometrically with modern techniques is that gap junction channels model of inactivation of voltage gated ionic can be split into connexons or hemi channels, whereby the carboxyl terminal channels using hyperosmotic disaccharide portion of connexin43 binds to CL, closing 23 solutions again implying that linkage is the channel. Higher order structure of the channel not covalent. is believed to consist of six connexins form ing the hemichannel or connexon in a 3.…

Seller Inventory # 9783662219379

Title
Gap Junctions in the Nervous System
Author
David C. Spray
Publisher
Springer, Berlin, Springer Berlin Heidelberg, Springer
Publication year
2013
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3662219379
ISBN 13
9783662219379
Item weight
638 grams
Dimensions
254x178x18 mm

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