Gap Junctions: Molecular Basis of Cell Communication in Health and Disease : Volume 49
Language: English
Published by Elsevier Science, 1999
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 191.62
Quantity: 2 available
Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to studying the molecular basis of membrane channel behavior. Twenty-eight comprehensive chapters, authored by internationally recognized leaders in the field, discuss the biophysical, physiological, and molecular characteristics of cell-to-cell communication via gap junctions. Key aspects of molecular structure, formation, gating, conductance, and permeability of vertebrate and invertebrate gap junction channels are highlighted. In addition, a number of chapters focus on recent discoveries that implicate connexin mutations and alterations of gap junctional communication in the pathogenesis of several diseases, including the X-linked Charcot-Marie-Tooth demyelinating disease, some forms of inherited sensorineural deafness, malignant transformation, cardiac malformations and arrhythmia, eye lens cataract, and Chagas disease.…
Seller Inventory # 9780125506458
- Title
- Gap Junctions: Molecular Basis of Cell Communication in Health and Disease : Volume 49
- Author
- Dale J Benos
- Publisher
- Elsevier Science
- Publication year
- 1999
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 0125506457
- ISBN 13
- 9780125506458
- Item weight
- 885 grams
- Dimensions
- 227x151x26 mm
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