Functions of the Natural Immune System

R. H. Wiltrout

ISBN 10: 146128046X / ISBN 13: 9781461280460

Published by Springer US, Chapman And Hall/CRC Mär 2013, 2013

About this Item

This item is printed on demand - it takes 3-4 days longer - Neuware -InhaltsangabeI. Role of the Natural Immune System in the Control of Tumor Cell Growth.- 1 Role of the Natural Immune System in Control of Primary Tumors and Metastasis.- 1. Introduction.- 2. Role of NK Cells in Host Resistance to Primary-Tumor Growth.- 3. NK Cells and Metastatic Growth.- 4. Role of NK Cells in the Antimetastatic Effects of Anticoagulant Drugs.- 5. Major Histocompatibility Complex (MHC) Antigen Expression and NK Sensitivity of Tumor Cells.- 6. Role in Immune Surveillance against Tumors.- 7. Stimulation of Natural Cell-Mediated Immunity and Treatment of Tumor Metastases.- References.- 2 Lymphokine-Activated Killer Cells: Biology and Therapeutic Efficacy.- 1. Introduction.- 2. Characterization and in Vitro Activity of Murine Lymphokine-Activated Killer Cells.- 3. Adoptive Immunotherapy in Murine Tumor Models.- 4. Mechanisms of Adoptive Immunotherapy and Toxicity in the Murine Model.- 5. Characterization of Human Lymphokine-Activated Killer Cells.- 6. Clinical Trials of Lymphokine-Activated Killer Cells and IL-2 in the Therapy of Metastatic Cancer.- 7. Future Prospects and Conclusions.- References.- Summary of Part I.- II. Involvement of the NIS in the Control of Microbial Iinfections.- 3 Natural Effector Cells in Influenza Virus Infection.- 1. Historical Perspective of NK Cells and Influenza Infection.- 2. Interferon and Influenza Infection.- 3. Role of NK Cells during Influenza Virus Infection.- 4. Pathological Consequences of NK Activity.- 5. Conclusions.- References.- 4 Natural Host Defense Systems Active against Herpes Simplex Virus Infections.- 1. Introduction.- 2. Mouse Studies.- 3. Human Studies.- 4. Conclusions.- References.- 5 Factors Influencing the Control of Virus Infections by Natural Killer Cells.- 1. Introduction.- 2. NK-Resistant and NK-Sensitive Viruses.- 3. Age-Dependent Resistance.- 4. Site of Virus Replication.- 5. Interferon-Mediated Effects on Target Cells.- 6. Mechanisms of Selective Lysis of Virus-Infected Target Cells by NK Cells.- 7. Use of NK Cells to Treat Virus Infections.- References.- 6 Natural Killer Cell-Mediated Resistance to Animal Parasites.- 1. Introduction.- 2. Interactions between Natural Killer Cells and Parasites.- 3. Parasites and Antibody-Facilitated Killer Cells.- 4. Conclusions.- References.- 7 Natural Host Resistance Mechanisms against Systemic Mycotic Agents.- 1. Introduction.- 2. Role of Monocytes/Macrophages in Host Defense.- 3. Role of Polymorphonuclear Leukocytes in Host Defense.- 4. Natural Killer Cells and Other Nonphagocytic Effector Cells in Host Defense.- 5. Summary.- References.- 8 Role of Natural Killer Cells in Inflammation and Antibacterial Activity.- 1. Introduction.- 2. Locomotion of Large Granular Lymphocytes.- 3. In Vivo Migratory Responses for Large Granular Lymphocytes/NK Cells.- 4. Can NK Cells Regulate the Inflammatory Response .- 5. Do NK Cells Have Antibacterial Activity .- 6. Concluding Remarks.- References.- Summary of Part II.- III. Immunoregulatory Properties of the NIS.- 9 Role of the Natural Immune System in the Antibody Response: Regulatory Effect of NK Cells.- 1. Introduction.- 2. B Cell Differentiation and Antibody Response.- 3. Evidence for Regulation of Antibody Response by NK Cells.- 4. Cellular Interaction in NK Regulation of B Cell Differentiation and Ig Secretion.- 5. Production of Cytokines by NK Cells and Their Role in the Regulation of Antibody Response.- 6. Conclusions and Summary.- References.- 10 Role of Natural Effector Cells in the Regulation of Cell-Mediated Immune Responses.- 1. Introduction.- 2. Characteristics of Natural Immunoregulatory Effector Cells.- 3. Regulation of Cell-Mediated Immune Functions.- 4. Relevance to Disease States.- 5. Summary and Future Directions.- References.- 11 Control of Hematopoietic Progenitor Cells by Natural Killer Cells.- 1. Introduction.- 2. Experimental and Clinical in Vivo Evidence for a Role of NK Cells in Regulatio.

Seller Inventory # 9781461280460

Bibliographic Details

• Title: Functions of the Natural Immune System
• Publisher: Springer US, Chapman And Hall/CRC Mär 2013
• Publication Date: 2013
• Language: English
• ISBN 10: 146128046X
• ISBN 13: 9781461280460
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 229W x 152H x 28D millimeters 229 millimeters width by 152 millimeters height by 28 millimeters depth
• Weight: 728 grams

About this title

Synopsis

Twenty contributions examine a variety of functions reportedly mediated by cells within the natural immune system and review the diverse functional activities of the lymphoid cells. Major emphasis is on the reactivity of natural effector cells specifically within the lymphoid populations. Annotation

Synopsis

Twenty contributions examine a variety of functions reportedly mediated by cells within the natural immune system and review the diverse functional activities of the lymphoid cells. Major emphasis is on the reactivity of natural effector cells specifically within the lymphoid populations. Annotation copyright Book News, Inc. Portland, Or.