Functional Coherence of Molecular Networks in Bioinformatics

Language: English

Published by Springer New York, Springer US Sep 2011, 2011

1461403197 / 9781461403197

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This item is printed on demand - it takes 3-4 days longer - Neuware -A fundamental problem in life sciences is the characterization of biological function. In medical sciences, understanding the bases of functional anomalies holds the key to effective diagnosis, treatment, and prognosis; in genetics, functional annotation of genetic variability uncovers the complex relationship between genotype and phenotype; in evolutionary biology, functional differences between diverse organisms highlight the evolutionary mechanisms that underlie the complexity of biological systems. With the successful completion of the human genome project and recent technological advances in biological data collection, it has become possible to study biological function from a systems perspective. Today, Systems Biology is established as a fundamental interdisciplinary science, which focuses on systematic study of the complex mechanisms that orchestrate the cooperation between diverse molecules that compose life.In the study of biological systems, the complex interactions between biomolecules are often abstracted using network models. Molecular networks provide descriptions of the organization of various biological processes, including cellular signaling, metabolism, and genetic regulation. Knowledge on molecular networks provides the basis for systems level analysis of biological function. Research and method development for such analyses has grown tremendously in the past few years. This volume provides a detailed overview of existing knowledge on the functional characterization of biological networks. In eight chapters authored by an international group of systems biology and bioinformatics researchers, functional coherence of molecular networks is comprehensively explored from various perspectives, including network topology, modularity, functional inference, evolution, phenotype, disease, network dynamics, and molecular kinetics. 240 pp. Englisch.…

Seller Inventory # 9781461403197

Title
Functional Coherence of Molecular Networks in Bioinformatics
Author
Mehmet Koyutürk
Publisher
Springer New York, Springer US Sep 2011
Publication year
2011
Condition
Neu
Binding
Buch
Language
English
ISBN 10
1461403197
ISBN 13
9781461403197
Item weight
530 grams
Dimensions
241x160x18 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

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