Frontiers in Radiation Oncology

Language: English

Published by Intechopen Jul 2013, 2013

9535111639 / 9789535111634

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -The mode of action by radiation is postulated to be the production of double strand breaks of DNA. The repair of double strand breaks occurs through non homologous end joining through acetylation of histone proteins by histone acetyltransferases (HATs). The fixation of double strand breaks through HAT inhibitors is a promising application for radiation sensitization in the clinic.P53 is a tumour suppressor gene and its mutation has been implicated in 60% of human cancers. As one of the pivotal anticancer genes, P53 controls the transcription and translation of a series of genes. The kinetics of DNA double strand break generation and their co relation to P53 status, ATM and ARF activation are computed and modelled for understanding the potential of such research. 228 pp. Englisch.

Seller Inventory # 9789535111634

Title
Frontiers in Radiation Oncology
Author
Tejinder Kataria
Publisher
Intechopen Jul 2013
Publication year
2013
Condition
Neu
Binding
Buch
Language
English
ISBN 10
9535111639
ISBN 13
9789535111634
Item weight
710 grams
Dimensions
266x185x20 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany