Formulation Of Phenytoin Complexes For Dissolution Enhancement
Language: English
Published by LAP LAMBERT Academic Publishing Mai 2014, 2014
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 53.13
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -Phenytoin Inclusion complex prepared by microwave method was used for preparation of FDT by different superdisintegrants by direct compression method. From that the cross-povidone (5%) containing inclusion complex was maximum DT, Wetting time and In-vitro drug release. The FDT containing 1:2 ratio complexes and 5% crospovidone give minimum DT and Wetting time. Then 32 full factorial designs were applied and the tablets were synthesized using different proportions of inclusion complex and crospovidone (%) by direct compression technique. The optimum ratio was 1:2 and 5% which produced highest DT (10.01 sec), Wetting time (9.45 sec.) and cumulative percent drug release (99.51% at 40 min). The solubility and dissolution pattern of Phenytoin were found to be carrier ratio dependent. From evaluation parameters and formulation characterization, it can be concluded that solubility of drug was improved by MW method compared to SE method and pure drug. The tablet contain optimum ratio of inclusion complex and optimum concentration of superdisintegrants give maximum drug release in minimum time period. 152 pp. Englisch.…
Seller Inventory # 9783659537059
- Title
- Formulation Of Phenytoin Complexes For Dissolution Enhancement
- Author
- Patel Maulika
- Publisher
- LAP LAMBERT Academic Publishing Mai 2014
- Publication year
- 2014
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3659537055
- ISBN 13
- 9783659537059
- Item weight
- 244 grams
- Dimensions
- 220x150x10 mm
"Synopsis" may belong to another edition of this title.
About the Author
"About the title" may belong to another edition of this title.
BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
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| Item | 5 to 15 business days | 5 to 15 business days |
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BuchWeltWeit Ludwig Meier e.K.
Germany
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