Formulation and Evaluation of Glipizide Solid Dispersion

Language: English

Published by LAP Lambert Academic Publishing, 2013

3659354368 / 9783659354366

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - More than 90% of the drugs arrowed since 1995 have poor solubility, poor permeability and more than 40% of new chemical entities have little or no water solubility. Glipizide is a class-II drug which is poorly soluble. So the solubility of the drug is enhanced by solid dispersion using solvent evaporation method. Drug and carrier in different ratios like 1: 1, 1: 2, 1: 3 by keeping drug weight constant. The prepared solid dispersions were evaluated for their routine tests like Phase solubility, Invitro dissolutoion study and the results were observed and tabulated. FT-IR study was also done for drug, polymers and 1: 3 ratios of drug: carrier by KBr pelleting method. From the study it was confirmed that no physical interactions were found. Also from the study it was concluded that 1: 3 ratio of drug:carrier shows better phase solubility and invitro dissolution rate.

Seller Inventory # 9783659354366

Title
Formulation and Evaluation of Glipizide Solid Dispersion
Author
M. R. Shivalingam
Publisher
LAP Lambert Academic Publishing
Publication year
2013
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659354368
ISBN 13
9783659354366
Item weight
142 grams
Dimensions
220x150x33 mm

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

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