Formulation and Development of Cefixime Trihydrate Floating Tablets

Language: English

Published by LAP LAMBERT Academic Publishing Dez 2020, 2020

6203196134 / 9786203196139

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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Softcover

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This item is printed on demand - it takes 3-4 days longer - Neuware -The purpose of this research is to develop the hydro-dynamically balanced delivery system of Cefixime Trihydrate for the localized action in the stomach, in the treatment of H.pylori mediated peptic ulcer. By applying wet granulation technique floating tablets of cefixime trihydra is prepare. Drug-Excipient compatibility study is performed by FTIR and DSC .Eudragit RS 100 polymer is use for maintaining drug release, % drug release, floating lag time and swelling index. The formulation developed using Cefixime trihydrate, Eudragit RS100, sodium bicarbonate gave floating lag time with a floating time of 12 h, and an in vitro release profile very near to the desired release. In vivo radiographic studies performed with Barium sulphate loaded formulation suggest that the tablet increase gastric residence time for the effective localized action of the antibiotic (Cefixime trihydrate) in the treatment of peptic ulcer. 104 pp. Englisch.…

Seller Inventory # 9786203196139

Title
Formulation and Development of Cefixime Trihydrate Floating Tablets
Author
Binapani Barik
Publisher
LAP LAMBERT Academic Publishing Dez 2020
Publication year
2020
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6203196134
ISBN 13
9786203196139
Item weight
173 grams
Dimensions
220x150x7 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

Shipping rates from Germany to U.S.A.

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BuchWeltWeit Ludwig Meier e.K.

Germany