Formulation and Development of Cefixime Trihydrate Floating Tablets : Cefixime trihydrate floating tablets for the treatment of peptic ulcer
Language: English
Published by LAP LAMBERT Academic Publishing, 2020
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 52.80
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Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - The purpose of this research is to develop the hydro-dynamically balanced delivery system of Cefixime Trihydrate for the localized action in the stomach, in the treatment of H.pylori mediated peptic ulcer. By applying wet granulation technique floating tablets of cefixime trihydra is prepare. Drug-Excipient compatibility study is performed by FTIR and DSC .Eudragit RS 100 polymer is use for maintaining drug release, % drug release, floating lag time and swelling index. The formulation developed using Cefixime trihydrate, Eudragit RS100, sodium bicarbonate gave floating lag time with a floating time of 12 h, and an in vitro release profile very near to the desired release. In vivo radiographic studies performed with Barium sulphate loaded formulation suggest that the tablet increase gastric residence time for the effective localized action of the antibiotic (Cefixime trihydrate) in the treatment of peptic ulcer.
Seller Inventory # 9786203196139
- Title
- Formulation and Development of Cefixime Trihydrate Floating Tablets : Cefixime trihydrate floating tablets for the treatment of peptic ulcer
- Author
- Binapani Barik
- Publisher
- LAP LAMBERT Academic Publishing
- Publication year
- 2020
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 6203196134
- ISBN 13
- 9786203196139
- Item weight
- 173 grams
- Dimensions
- 220x150x7 mm
"Synopsis" may belong to another edition of this title.
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