Factorial Design: A Comparative Study With And Without Use of Software : A Comparative Factorial Design Approach In Pharmaceutical Formulations

Language: English

Published by LAP LAMBERT Academic Publishing, 2015

3659460117 / 9783659460111

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Factorial design as optimization technique was applied in formulation development and processing conditions of Diclofenac sodium granules. The present study involves design and evaluation of non-effervescent granules of Diclofenac sodium with excellent flow properties. In the formulation of non-effervescent granules of Diclofenac sodium, angle of repose was the dependent variable (with excellent flow) and the concentrations of binder (Povidone K-30) and lubricant (Magnesium stearate) were the two independent variables chosen at two different levels. With the help of factorial approach, a polynomial equation Y= B0 + B1X1 + B2X2 + B12X1X2 was formed. Using the polynomial equation three new formulations were selected and performed to evaluate the correlation between experimental and predicted responses. A good correlation was obtained between the experimental and the predicted values. Also the work was oriented to have a comparative study of application of factorial design with and without use of software and come up with any pros and cons of these respective ways.…

Title
Factorial Design: A Comparative Study With And Without Use of Software : A Comparative Factorial Design Approach In Pharmaceutical Formulations
Author
Priyank Parikh
Publisher
LAP LAMBERT Academic Publishing
Publication year
2015
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659460117
ISBN 13
9783659460111
Item weight
131 grams
Dimensions
220x150x6 mm

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