Extrasynaptic GABAA Receptors

Language: English

Published by Springer New York Sep 2014, 2014

1493914251 / 9781493914258

Series: Book 20 of 29 - The Receptors

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed 'tonic' inhibition, has been described. Whereas synaptic GABAA receptors underlie classical 'phasic' GABAA receptor-mediated inhibition (inhibitory postsynaptic currents), tonic GABAA receptor-mediated inhibition results from the activation of extrasynaptic receptors by low concentrations of ambient GABA. Extrasynaptic GABAA receptors are composed of receptor subunits that convey biophysical properties ideally suited to the generation of persistent inhibition and are pharmacologically and functionally distinct from their synaptic counterparts. This book highlights ongoing work examining the properties of recombinant and native extrasynaptic GABAA receptors and their preferential targeting by endogenous and clinically relevant agents. In addition, it emphasizes the important role of extrasynaptic GABAA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes. 308 pp. Englisch.…

Seller Inventory # 9781493914258

Title
Extrasynaptic GABAA Receptors
Author
Adam C. Errington
Publisher
Springer New York Sep 2014
Publication year
2014
Condition
Neu
Binding
Buch
Language
English
ISBN 10
1493914251
ISBN 13
9781493914258
Item weight
629 grams
Dimensions
241x160x21 mm
Series
Book 20 of 29: The Receptors

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

Shipping rates from Germany to U.S.A.

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BuchWeltWeit Ludwig Meier e.K.

Germany