Extraction and Crystal Structure of Physalin B

Language: English

Published by LAP LAMBERT Academic Publishing Mai 2017, 2017

3330082232 / 9783330082236

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This item is printed on demand - it takes 3-4 days longer - Neuware -Physalin B (C28H32O9), a main active physalin of Physalis angulata L was isolated from the whole plant of Physalis angulata L, and characterized by X-ray diffraction analysis. It crystallizes in the monoclinic system, space group P2(1) with C28H32O9, a = 12.4996(2), b = 14.35620(10), c = 14.75190(10)Å, V = 2607.97(5)Å3, Z = 4,Dc = 1.382mg/cm3, Mr = 542.56, F(000) = 1152, and mi= 0.870 mm-1. The final R = 0.0389 and wR = 0.1037 for 47670 observed reflections (I 2 (I)). The rigid molecule consists of eight fused rings involving two lactones. There are two C28H32O9 molecules in an symmetric unit, and the title compound is stacked into a 3D layer structure through hydrogen bonds.In the 5-20mimol/L range, physalin B can significantly inhibit the secretion of inflammatory cytokines TNF- and IL-6 on RAW264.7 cells. The results suggest that physalin B has anti-inflammatory activity in vitro. 60 pp. Englisch.

Seller Inventory # 9783330082236

Title
Extraction and Crystal Structure of Physalin B
Author
Yan-Jun Yang
Publisher
LAP LAMBERT Academic Publishing Mai 2017
Publication year
2017
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3330082232
ISBN 13
9783330082236
Item weight
107 grams
Dimensions
220x150x4 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

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BuchWeltWeit Ludwig Meier e.K.

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