Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications provides comprehensive coverage on not only the biosynthesis, isolation, purification, and functionalization of extracellular vesicles for therapeutic and diagnostic applications, but also current trends in functionalized extracellular vesicles for biomedical research and commercial-scale opportunities. Sections focus on the fundamental aspects of extracellular vesicles, covering their origin, classification, biosynthesis, isolation techniques, purification challenges, and functionalization for biomedical applications, while also delving into the therapeutic applications of extracellular vesicles and their role in treating diseases.
Content also address biocompatibility, safety, translation challenges, biocompatibility, and translation challenges. Final sections explore the diagnostic potential of extracellular vesicles in biomedical research, highlighting their role as diagnostic biomarkers in various diseases. Emerging technologies and future directions in extracellular vesicle research round out the content, making it a valuable reference for researchers and clinicians seeking an in-depth understanding of extracellular vesicles and their potential biomedical applications.
- Discusses fundamentals and explains the biosynthesis, isolation, purification, and functionalization techniques of extracellular vesicles
- Delves into recent advances of extracellular vesicles-based biovectors for biomedical applications in therapeutics and diagnostics
- Explores the future of extracellular vesicle research, including emerging technologies for extracellular vesicle manipulation, novel bioengineering approaches, and the potential of extracellular vesicles in personalized medicine
Dr. Arun Kumar is currently an Assistant Professor in the Department of Pharmacy at Central University of South Bihar, Gaya, India. He earned a PhD from the Department of Pharmacy at Jaypee University of Information Technology, Waknaghat, Solan, India. He has more than 11 years of combined research and teaching experience, and his work focuses on smart and responsive materials, 3D printing, microneedles, extracellular-based drug delivery, antimicrobial compounds, and nanostructures for various biomedical applications, including tissue regeneration, drug delivery, and cancer therapy. He has actively collaborated with researchers in other disciplines of pharmaceutical sciences, particularly the nanoformulations of drugs for drug delivery systems and nanomedicine. His work has resulted in the publication of over 60 peer-reviewed journal articles in prestigious journals, including International Journal of Biological Macromolecules, Advanced Healthcare Materials, Seminars in Cancer Biology, Journal of Material Chemistry B, and Bioengineering and Translational Medicines. He has also author over five book chapters and has files five patents filed.
Dr. Charan Singh is currently an Assistant Professor of Pharmaceutics at HNB Garhwal University (A Central University), Srinagar Garhwal, Uttarakhand, India. He received his PhD in Pharmaceutical Technology (Formulation) from the National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar, Punjab, India. He was later a National Postdoc Fellow at Panjab University, Chandigarh, India and an IBRO-Exchange Fellow at the University of Queensland in Brisbane, Australia. He has received a number of other fellowships and awards such as the IBRO Early Career Award and the SERB-SIRE Fellowship. Dr. Singh’s research interests include the design, synthesis, characterization, and evaluation of lipidic and polymeric nanomaterials for drug delivery and targeting to improve the treatment and diagnosis of human diseases. Dr. Singh has one patent (granted) and has published book chapters and more than 50 publications in international journals such as Journal of Controlled Release, Asian Journal of Pharmaceutical Sciences, Carbohydrate Polymers, Drug Delivery Sciences and Technology, International Journal of Pharmaceutics.
Dr. Ajeet Kaushik is an Associate Professor of Chemistry at the Department of Chemistry, at Florida Polytechnic University, Florida, United States, as well as an ICS Fellow and Fulbright Specialist. Currently he is exploring nano-enabled technologies for health and environmental monitoring. He has authored or co-authored over 350 publications, published 14 edited books, and has 4 patents, as well as various other editorial roles and international collaborations. Dr. Kaushik’s research interests include green chemistry, catalysis, drug delivery systems, electrochemistry, sensors, and point-of-care sensing for sustainable health and the environment.
