Excited State Dynamics in DNA and RNA : Experimental and Computational Studies on the Triplet State
Language: English
Published by Wiley-VCH Gmbh Apr 2026, 2026
- Hardcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
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Neuware - Focusses on the excited triplet states within DNA and RNA with combined experimental and computational approaches.
Seller Inventory # 9783527354672
- Title
- Excited State Dynamics in DNA and RNA : Experimental and Computational Studies on the Triplet State
- Author
- Jinquan Chen
- Publisher
- Wiley-VCH Gmbh Apr 2026
- Publication year
- 2026
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 3527354670
- ISBN 13
- 9783527354672
- Item weight
- 639 grams
- Dimensions
- 251x179x22 mm
Presents comprehensive insights into triplet excited state dynamics of DNA and RNA across experiment and theory
Understanding the excited state dynamics of DNA and RNA is fundamental to addressing both the detrimental and beneficial consequences of UV light on biological systems. While the triplet excited state is a precursor to damaging pathways such as photodamage, mutation, and carcinogenesis, it also offers opportunities for developing targeted therapies through DNA-targeted photosensitizing drugs. Despite its dual role, no single resource has systematically synthesized the experimental and theoretical progress in this field.
Excited State Dynamics in DNA and RNA: Experimental and Computational Studies on the Triplet State provides the first comprehensive overview of this rapidly growing interdisciplinary area, bridging photochemistry, photobiology, and photomedicine. Beginning with a historical overview of the field, the volume progresses to cover triplet dynamics in canonical and noncanonical nucleobases, triplet-mediated photochemistry, and drug-sensitized processes in DNA. Later chapters examine cutting-edge computational photobiology and quantum mechanical simulations, highlighting how molecular structure and environment influence excited state behaviors.
Offering a holistic perspective on mechanisms underpinning UV-induced damage and therapeutic opportunities, Excited State Dynamics in DNA and RNA:
- Integrates photochemistry, photobiology, and photomedicine into a unified resource
- Presents experimental findings alongside theoretical models
- Highlights experimental advances in spectroscopy and ultrafast dynamics
- Includes computational studies using ab initio and surface-hopping dynamics simulations
- Addresses both canonical and epigenetically modified nucleobases.
- Explores implications for drug-sensitized DNA triplet states and photoactivated therapies.
- Synthesizes current research trends into a pedagogical framework accessible to non-specialists
Excited State Dynamics in DNA and RNA: Experimental and Computational Studies on the Triplet State is an essential resource for graduate-level and advanced undergraduate courses in molecular biophysics, photochemistry, and chemical biology. It is also a key reference for researchers and professionals working in molecular biology, biophysics, medicinal chemistry, and photomedicine.
"Synopsis" may belong to another edition of this title.
About the Author
Jinquan Chen, PhD, is Full Professor, State Key Laboratory of Precision Spectroscopy, East China Normal University (ECNU), Shanghai, China. His research focuses on developing femtosecond time-resolved spectroscopy techniques to investigate excited state dynamics in biomolecules, with particular emphasis on the photophysics and photochemistry of epigenetic nucleic acids and their triplet excited states. He has published over 130 journal articles, serves on the Early Career Researcher Editorial Board of the Chinese Journal of Chemical Physics, and is Vice-President of the Shanghai Biophysics Society.
"About the title" may belong to another edition of this title.
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