Excitation-Contraction Coupling and Cardiac Contractile Force
Language: English
Published by Springer Netherlands Aug 2001, 2001
Series: Book 210 of 253 - Developments in Cardiovascular Medicine
- Hardcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 184.50
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -How is the heartbeat generated What controls the strength of contraction of heart muscle What are the links between cardiac structure and function How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart Are there important species differences in how contraction is regulated in the heart How do the new molecular data fit together in understanding the heart beat What goes wrong in ischemia, hypertrophy, and heart failure This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). Excitation-Contraction Coupling and Cardiac Contractile Force &endash; Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields. 454 pp. Englisch.…
Seller Inventory # 9780792371571
- Title
- Excitation-Contraction Coupling and Cardiac Contractile Force
- Author
- Donald Bers
- Publisher
- Springer Netherlands Aug 2001
- Publication year
- 2001
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 0792371577
- ISBN 13
- 9780792371571
- Edition
- 2nd Edition
- Item weight
- 843 grams
- Dimensions
- 241x160x29 mm
- Series
- Book 210 of 253: Developments in Cardiovascular Medicine
The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure).
Excitation-Contraction Coupling and Cardiac Contractile Force &endash; Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.
"Synopsis" may belong to another edition of this title.
Review
W. Jonathan Lederer (excerpted from the Introduction).
`This second edition of a now classical text is both extensively revised and up-to-date. The many illustrations, a large number of which are new to this edition, supplement a clearly written text that is filled with useful information. For those who seek a lucid, comprehensive and authoritative description of the interlocked systems that control the heart beat, I know of no other source that approaches Bers' Excitation-Contraction Coupling and Cardiac Contractile Force.'
Arnold M. Katz
`This book is a breath of fresh (and educated and thoughtful and well-organized) air Don Bers has produced a remarkably approachable and informative volume, clearly superior to others in this field. Active researchers should buy this book for themselves and their students.'
Laurence L. Brunton
"About the title" may belong to another edition of this title.
BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
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BuchWeltWeit Ludwig Meier e.K.
Germany
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