Evolutionary Methods in Biotechnology. Dirty Tricks for Directed Evolution: Clever Tricks for Directed Evolution : Dirty Tricks for Directed Evolution
Language: English
Published by Wiley-VCH, 2004
- Hardcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
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Neu Auf Lager, Sofortversand per DHL/dpd aus Deutschland - Wie erstellt und durchsucht man kombinatorische Enzymbibliotheken Dieser Band stellt Ihnen erstmals geprüfte, ausführliche Protokolle zur Verfügung. Die Autoren der Beiträge, Experten mit eigener Erfahrung in der evolutionären Biotechnologie, kommentieren die Arbeitsanleitungen mit Hinweisen zu häufigen Fehlern und deren Beseitigung. Unentbehrlich fürjeden, der auf diesem interdisziplinären Gebiet arbeitet.
Seller Inventory # INF1000021187
- Title
- Evolutionary Methods in Biotechnology. Dirty Tricks for Directed Evolution: Clever Tricks for Directed Evolution : Dirty Tricks for Directed Evolution
- Author
- Susanne Brakmann,Andreas Schwienhorst
- Publisher
- Wiley-VCH
- Publication year
- 2004
- Condition
- Neu
- Binding
- Gebundene Ausgabe
- Language
- English
- ISBN 10
- 3527307990
- ISBN 13
- 9783527307999
- Item weight
- 572 grams
- Dimensions
- 248x176x17 mm
From library generation by random or directed mutagenesis to screening and selection techniques -- the crucial steps for successful evolutionary biotechnology are described in detail in this practical guide that also includes valuable troubleshooting hints on frequently encountered problems.
Modern methods for the surface display of peptides and proteins, selective enrichment of nucleic acid aptamers and high-throughput screening of industrial biocatalysts are explained, and computer-based methods for in silico protein and RNA engineering are described as an alternative to in vitro approaches. A special section covers the patenting regulations with regard to biotechnological innovations derived from directed evolution.
As an added bonus, a CD-ROM is included that contains software tools for library design, selection of mutagenesis positions, and various predictive algorithms.
In short, this practice oriented handbook is an indispensable tool for every scientist working in this interdisciplinary research area.
"Synopsis" may belong to another edition of this title.
About the Author
Andreas Schwienhorst is a group leader at the Institute of Microbiology and Genetics at the University of Gottingen (Germany). He was born in Warendorf and did his studies of Biochemistry and Prehistory in Munster and Gottingen. His thesis was carried out at the Max-Planck-Institute for Biophysical Chemistry under the supervision of Manfred Eigen. He was a visiting scientist at the Salk Institute, La Jolla and the Los Alamos National Laboratory (USA), then took a position as a group leader at the Institute for Molecular Biotechnology before moving to the University of Gottingen in 1997. In 1998 he received the Biofuture Award. Currently, he is interested in the discovery of novel targets for drug intervention as well as in methods of molecular evolution and their applications in drug discovery and catalysis.
"About the title" may belong to another edition of this title.
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