Evolution by Tumor Neofunctionalization

Andrei P Kozlov

ISBN 10: 0128001658 / ISBN 13: 9780128001653

Published by Elsevier Science Feb 2014, 2014

About this Item

This item is printed on demand - it takes 3-4 days longer - Neuware -Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution. Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution. This book will stimulate thinking on this topic by specialists in the fields of evolutionary biology, oncology, molecular biology, molecular evolution, embryology, evo-devo, tumor immunology, pathology and clinical oncology. 248 pp. Englisch.

Seller Inventory # 9780128001653

Bibliographic Details

• Title: Evolution by Tumor Neofunctionalization
• Publisher: Elsevier Science Feb 2014
• Publication Date: 2014
• Language: English
• ISBN 10: 0128001658
• ISBN 13: 9780128001653
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 228W x 149H x 20D millimeters 228 millimeters width by 149 millimeters height by 20 millimeters depth
• Weight: 504 grams

About this title

Synopsis

Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution. Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution. This book will stimulate thinking on this topic by specialists in the fields of evolutionary biology, oncology, molecular biology, molecular evolution, embryology, evo-devo, tumor immunology, pathology and clinical oncology.

Review

"...an excellent book that formulates the hypothesis of evolution by tumor neofunctionalization and presents interesting concepts related to the positive role of tumors in the evolution of multicellular organisms. It will be of immense interest to a diverse group of professionals...3 Stars - Score: 86" -Doody's.com, Nov 14, 2014