From Enzyme Models to Model Enzymes
Language: English
Published by Royal Society of Chemistry, GB, 2009
- Hardcover
- New
Seller: Rarewaves.com USA, London, London, United KingdomRarewaves.com USA
AbeBooks seller since June 11, 2025
Condition: New
£ 202.95
Quantity: Over 20 available
Add to basketItem description from seller
Designing artificial systems with catalytic efficiencies to rival those of natural enzymes is one of the great challenges facing science today. Our current level of understanding fails the basic, practical test - designing and making artificial systems with catalytic efficiencies to rival those of natural enzymes. Chemists and bio-scientists are well aware of this problem, and "artificial enzymes" have been a "hot topic" for many years. However, until now, there has been no book devoted specifically to this subject. This is the first book to provide a critical introduction to, and overview of, this exciting area. It is aimed at students and more senior researchers with specialist or general interests in the field. The book starts with a systematic overview of the most important properties of natural enzymes, with special emphasis on mechanisms and efficiency of catalysis. This is followed by a summary of the mechanisms involved in the major classes of reaction they catalyze, and spells out the logical progression from simple mechanistic models for particular reactions to the first, rudimentary artificial enzymes catalyzing them. Catalytic efficiency is the key criterion for inclusion. An analysis of the strengths and limitations of the classical design-based approach to catalysis by enzyme mimics leads on to a discussion of recent advances which use selection methods coupled with iterative techniques for creating and improving catalysts by natural methods. The comparison of natural and artificial catalysts requires a quantitative understanding based on the interpretation of kinetic measurements. Key skills in data interpretation are introduced in a guided approach that connects the formal treatment of kinetic measurements with their chemical and biological interpretation.…
Seller Inventory # LU-9780854041756
- Title
- From Enzyme Models to Model Enzymes
- Author
- Anthony J Kirby, Florian Hollfelder
- Publisher
- Royal Society of Chemistry, GB
- Publication year
- 2009
- Condition
- New
- Binding
- Hardback
- Language
- English
- ISBN 10
- 0854041753
- ISBN 13
- 9780854041756
- Item weight
- 571 grams
- Dimensions
- 15.6 x 1.98 x 23.4 cm
This introduction to the exciting area of artificial enzymes is suitable for students and more senior researchers.
"Synopsis" may belong to another edition of this title.
About the Author
Anthony J. Kirby is Professor (Emeritus) of Bioorganic Chemistry at the University of Cambridge. He has over 40 years teaching and research experience in the area and has authored over 300 papers and 3 books. Florian Hollfelder has been lecturing in Biochemistry since 2001. He has a total of 15 years teaching and research experience at Cambridge, Stanford & Harvard and has authored more than 30 papers.
"About the title" may belong to another edition of this title.
Rarewaves.com USA
London, London, United Kingdom
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