Title: Efficacit� de la combinaison Patients atteints de n�phropathie diab�tique (French Edition)
Publisher: Editions Notre Savoir
Publication Date: 2024
Language: French
ISBN 10: 6208342406
ISBN 13: 9786208342401
Binding: Soft cover
Condition: New

About this title

Synopsis

Il est essentiel de privil�gier la pr�vention plut�t que le traitement de la n�phropathie diab�tique. Une fois que la n�phropathie est manifeste, la progression ne peut �tre �vit�e, mais seulement retard�e. Le premier indicateur clinique des l�sions r�nales est la microalbuminurie, qui doit �tre d�pist�e � intervalles r�guliers � l'aide de tests sensibles. Plusieurs �tudes d�montrent l'effet pr�ventif d'une baisse de la glyc�mie sur les complications microvasculaires du diab�te, y compris la n�phropathie, et justifient l'importance accord�e � un contr�le glyc�mique rigoureux plut�t qu'occasionnel. Avant et surtout apr�s l'apparition d'une n�phropathie pr�coce, le contr�le de la pression art�rielle est essentiel pour pr�venir ou ralentir la progression des l�sions r�nales. Les agents de premier choix pour le traitement de la microalbuminurie sont les inhibiteurs de l'ECA. L'�nalapril a un effet antiprot�inurique ind�pendant de l'effet sur la pression art�rielle syst�mique. Le traitement � l'�nalapril peut r�duire le taux de d�clin de la fonction r�nale chez les patients atteints de n�phropathie diab�tique de mani�re plus importante qu'un traitement antihypertenseur d'efficacit� �gale � base de m�toprolol. Cela indique un effet protecteur r�nal sp�cifique des inhibiteurs de l'enzyme de conversion de l'angiotensine dans la n�phropathie diab�tique.

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