Ecto-ATPases

Language: English

Published by Springer US Okt 2012, 2012

1461377293 / 9781461377290

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -It has been known for almost 50 years that many cells carry enzymes that hydro lyze extracellular ATP, and the term 'ecto-ATPase' was used first by Engelhardt 40 years ago. But until the end of the 1970's, the idea of an ATPase with its ATP hydrolyzing site on the outside of the cell membrane was met with substantial skepticism since it was thought that ATP was strictly intracellular. Nevertheless, ecto-ATPase activity was dem onstrated using a variety of intact cells. Most ecto-ATPase(s) exhibited three common 2 characteristics: 1) activation by either Ca + or Mg2+, 2) insensitivity to the commonly used inhibitors ofF-type, P-type, and V-type ATPases, and 3) ability to hydrolyze nucleo side triphosphates and often nucleoside diphosphates as well. At the same time, the dominant ATPase activity in many plasma membrane preparations was shown to be dis tinct from the ion-pump ATPases, but had similar enzymatic properties as the ecto-AT Pase(s). Thus the term 'E-type ATPase activity' has been proposed for ATPase activity exhibiting these characteristics, and it is assumed that all ecto-ATPases are E-type AT Pases. The converse is not true, however, since soluble E-type ATPases were shown to ex sist in plants, microorganisms, and the saliva of blood sucking insects. These enzymes could be easily purified, and exhibited very high specific activity. 312 pp. Englisch.…

Seller Inventory # 9781461377290

Title
Ecto-ATPases
Author
Liselotte Plesner
Publisher
Springer US Okt 2012
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1461377293
ISBN 13
9781461377290
Item weight
590 grams
Dimensions
254x178x17 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

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