ESTUDIO RP- HPLC DE LA REBAMIPIDA
Language: Spanish
Published by Ediciones Nuestro Conocimiento Mrz 2021, 2021
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 34.66
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -El objetivo del presente trabajo fue desarrollar y validar un método sencillo de RP-HPLC para la determinación de Rebamipide. La separación cromatográfica de la Rebamipida se logró utilizando una columna C18. Se bombeó una fase móvil que contenía una mezcla de metanol: agua (70:30 v/v) a un caudal de 1 ml/min. La detección se realizó a 231 nm. Los parámetros de validación se evaluaron según las directrices Q2R1 de la Conferencia Internacional de Armonización (ICH). La curva de calibración fue lineal en el rango de concentración 2- 10¿g/ml para la Rebamipida con un coeficiente de regresión de 0,999. El método resultó ser preciso con un 0,66 % de RSD. Los valores de RSD resultaron ser del 0,94 % en el caso de los estudios de precisión intradiaria, mientras que el 0,76 % en el caso de la precisión intradiaria, los límites de detección y cuantificación resultaron ser de 0,6 y 1,98¿g/ml, respectivamente. Los resultados obtenidos de las pruebas de tensión revelan que la sustancia farmacológica Rebamipide es particularmente estable en condiciones de degradación ácida, neutra y térmica. Desde el punto de vista de la estabilidad, se debe tener cuidado en el proceso de fabricación y almacenamiento de este producto. El método se aplicó con éxito para el propósito de cuantificación y se encontró t 68 pp. Spanisch.…
Seller Inventory # 9786203395525
Bibliographic details
- Title
- ESTUDIO RP- HPLC DE LA REBAMIPIDA
- Author
- Biswajit Samantaray
- Publisher
- Ediciones Nuestro Conocimiento Mrz 2021
- Publication year
- 2021
- Condition
- Neu
- Dust jacket
- Dust Jacket Included
- Binding
- Taschenbuch
- Language
- Spanish
- ISBN 10
- 6203395528
- ISBN 13
- 9786203395525
- Item weight
- 119 grams
- Dimensions
- 220x150x5 mm
BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
Shipping rates from Germany to U.S.A.
| Item | 5 to 15 business days | 5 to 15 business days |
|---|---|---|
| First item | £ 19.39 | £ 19.39 |
Payment methods
- Bank Wire Transfer
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Seller's business information
BuchWeltWeit Ludwig Meier e.K.
Germany
Terms of sale
BuchWeltWeit Inh. Ludwig Meier e.K.
Inhaber: Ludwig Meier
De-Gasperi-Str. 8
51469 Bergisch Gladbach
Deutschland
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